Risk factors associated with indoor transmission during home quarantine of COVID-19 patients

Liu, Yang1; Chai, Yan-Hua1; Wu, Yi-Fan1; Zhang, Yu-Wei1; Wang, Ling1; Yang, Ling1; Shi, Yi-Han1; Wang, Le-Le1; Zhang, Li-Sha1; Chen, Yan1; Fan, Rui1; Wen, Yu-Hua1; Yang, Heng1; Li, Li2; Liu, Yi-Han1; Zheng, Hui-Zhen1; Jiang, Ji-Jin1; Qian, Hao1; Tao, Ru-Jia1; Qian, Ye-Chang2; Wang, Ling-Wei3,4; Chen, Rong-Chang3,4; Xu, Jin-Fu1; Wang, Chen5,6,7

2023-05-11

10.3389/fpubh.2023.1170085

FRONTIERS IN PUBLIC HEALTH   影响因子和分区

2296-2565

PurposeThe study aimed to identify potential risk factors for family transmission and to provide precautionary guidelines for the general public during novel Coronavirus disease 2019 (COVID-19) waves. MethodsA retrospective cohort study with numerous COVID-19 patients recruited was conducted in Shanghai. Epidemiological data including transmission details, demographics, vaccination status, symptoms, comorbidities, antigen test, living environment, residential ventilation, disinfection and medical treatment of each participant were collected and risk factors for family transmission were determined. ResultsA total of 2,334 COVID-19 patients participated. Compared with non-cohabitation infected patients, cohabitated ones were younger (p = 0.019), more commonly unvaccinated (p = 0.048) or exposed to infections (p < 0.001), and had higher rates of symptoms (p = 0.003) or shared living room (p < 0.001). Risk factors analysis showed that the 2019-nCov antigen positive (OR = 1.86, 95%CI 1.40-2.48, p < 0.001), symptoms development (OR = 1.86, 95%CI 1.34-2.58, p < 0.001), direct contact exposure (OR = 1.47, 95%CI 1.09-1.96, p = 0.010) were independent risk factors for the cohabitant transmission of COVID-19, and a separate room with a separate toilet could reduce the risk of family transmission (OR = 0.62, 95%CI 0.41-0.92, p = 0.018). ConclusionPatients showing negative 2019-nCov antigen tests, being asymptomatic, living in a separate room with a separate toilet, or actively avoiding direct contact with cohabitants were at low risk of family transmission, and the study recommended that avoiding direct contact and residential disinfection could reduce the risk of all cohabitants within the same house being infected with COVID-19.

COVID-19 omicron indoor transmission risk factor home quarantine

SCI ; SSCI

英语

通讯

Public, Environmental & Occupational Health

Public, Environmental & Occupational Health

WOS:000993406700001

FRONTIERS MEDIA SA

Web of Science

1.Tongji Univ, Inst Resp Med, Sch Med, Shanghai, Peoples R China
2.Baoshan Dist Hosp Integrated Tradit Chinese & West, Dept Resp Med, Shanghai, Peoples R China
3.Jinan Univ, Southern Univ Sci & Technol, Shenzhen Peoples Hosp, Affiliated Hosp 1,Clin Med Coll 2,Shenzhen Inst Re, Shenzhen, Peoples R China
4.Shenzhen Peoples Hosp, Shenzhen Clin Res Ctr Respirol, Shenzhen, Peoples R China
5.Natl Ctr Resp Med, Beijing, Peoples R China
6.Natl Clin Res Ctr Resp Dis, Beijing, Peoples R China
7.Chinese Acad Med Sci, Inst Resp Med, Peking Union Med Coll, Beijing, Peoples R China

Liu, Yang,Chai, Yan-Hua,Wu, Yi-Fan,et al. Risk factors associated with indoor transmission during home quarantine of COVID-19 patients[J]. FRONTIERS IN PUBLIC HEALTH,2023,11.

Liu, Yang.,Chai, Yan-Hua.,Wu, Yi-Fan.,Zhang, Yu-Wei.,Wang, Ling.,...&Wang, Chen.(2023).Risk factors associated with indoor transmission during home quarantine of COVID-19 patients.FRONTIERS IN PUBLIC HEALTH,11.

Liu, Yang,et al."Risk factors associated with indoor transmission during home quarantine of COVID-19 patients".FRONTIERS IN PUBLIC HEALTH 11(2023).