Selective adsorption of trace morpholine impurities over N-ethyl morpholine by tetralactam solids

Li，Shi Yao1; Yao，Huan1; Hu，Hao1; Chen，Wen Jie1; Yang，Liu Pan1,2; Wang，Li Li1

2023

10.1039/d3cc01164j

Chemical Communications   影响因子和分区

1359-7345

1364-548X

The separation and especially the removal of morpholine (MOR) impurities from N-ethyl morpholine (NEM) is of great significance in the fine chemical industry. Herein, we offer a novel strategy for the selective adsorption of MOR over NEM by tetralactam solids. The adsorbent realized the purification of NEM by adsorbing traces of MOR impurities, such that the purity can be improved from around 98% to over 99.5%. Single crystal structures indicate that N-H⋯O and N-H⋯N hydrogen bonding interactions are essential in the selective separation.

SCI

英语

NI论文

其他

National Natural Science Foundation of China["22174059","22201128"] ; Natural Science Foundation of Hunan Province, China["2022JJ40363","2022JJ40365","2022RC1230"] ; Department of Education of Guangdong Province[2020ZDZX2060]

Chemistry

Chemistry, Multidisciplinary

WOS:000993807100001

ROYAL SOC CHEMISTRY

CHEMISTRY

2-s2.0-85160427390

Scopus

1.School of Pharmaceutical Science,Hengyang Medical School,University of South China,Hengyang,Hunan,421001,China
2.Department of Chemistry,Southern University of Science and Technology,Shenzhen,Xueyuan Blvd 1088,518055,China

Li，Shi Yao,Yao，Huan,Hu，Hao,et al. Selective adsorption of trace morpholine impurities over N-ethyl morpholine by tetralactam solids[J]. Chemical Communications,2023,59(47).

Li，Shi Yao,Yao，Huan,Hu，Hao,Chen，Wen Jie,Yang，Liu Pan,&Wang，Li Li.(2023).Selective adsorption of trace morpholine impurities over N-ethyl morpholine by tetralactam solids.Chemical Communications,59(47).

Li，Shi Yao,et al."Selective adsorption of trace morpholine impurities over N-ethyl morpholine by tetralactam solids".Chemical Communications 59.47(2023).