Endoscopic mucosal resection with double band ligation versus endoscopic submucosal dissection for small rectal neuroendocrine tumors

Huang, Jia-Lan1; Gan, Ri-Yun1; Chen, Ze-Han1; Gao, Ruo-Yu2; Li, De-Feng3,4; Wang, Li-Sheng3,4; Yao, Jun3,4,5,6

2023-03-27

10.4240/wjgs.v15.i3.440

WORLD JOURNAL OF GASTROINTESTINAL SURGERY   影响因子和分区

1948-9366

["BACKGROUND Endoscopic resection remains an effective method for the treatment of small rectal neuroendocrine tumors (NETs) (<= 10 mm). Moreover, endoscopic mucosal resection (EMR) with double band ligation (EMR-dB), a simplified modification of EMR with band ligation, is an alternative strategy to remove small rectal NETs.","AIM To evaluate the feasibility and safety of EMR-dB for the treatment of small rectal NETs (<= 10 mm).","METHODSA total of 50 patients with small rectal NETs, without regional lymph node enlargement or distant metastasis confirmed by endoscopic ultrasound, computerized tomography scan, or magnetic resonance imaging, were enrolled in the study from March 2021 to June 2022. These patients were randomly assigned into the EMR-dB (n = 25) group or endoscopic submucosal dissection (ESD) group (n = 25). The characteristics of the patients and tumors, procedure time, devices cost, complete resection rate, complications, and recurrence outcomes were analyzed.","RESULTS There were 25 patients (13 males, 12 females; age range 28-68 years old) in the EMR-dB group, and the ESD group contained 25 patients (15 males, 10 females; age range 25-70 years old). Both groups had similar lesion sizes (EMR-dB 4.53 +/- 1.02 mm, ESD 5.140 +/- 1.74 mm; P = 0.141) and resected lesion sizes(1.32 +/- 0.52 cm vs 1.58 +/- 0.84 cm; P = 0.269). Furthermore, the histological complete resection and en bloc resection rates were achieved in all patients (100% for each). In addition, there was no significant difference in the complication rate between the two groups. However, the procedure time was significantly shorter and the devices cost was significantly lower in the EMR-dB group. Besides, there was no recurrence in both groups during the follow-up period.","CONCLUSION The procedure time of EMR-dB was shorter compared with ESD, and both approaches showed a similar curative effect. Taken together, EMR-dB was a feasible and safe option for the treatment of small rectal NETs."]

Small rectal neuroendocrine tumor Endoscopic submucosal dissection Endoscopic mucosal resection Ligation complete resection rate Complication

SCI

英语

通讯

Technical Research and Development Project of Shenzhen[JCYJ20210324113215040]

Gastroenterology & Hepatology ; Surgery

Gastroenterology & Hepatology ; Surgery

WOS:000982163700012

BAISHIDENG PUBLISHING GROUP INC

Web of Science

1.Jinan Univ, Clin Med Coll 2, Dept Gastroenterol, Shenzhen 518020, Guangdong Provi, Peoples R China
2.Shenzhen Luohu Peoples Hosp, Dept Gastroenterol, Shenzhen 518020, Guangdong Provi, Peoples R China
3.Jinan Univ, Shenzhen Peoples Hosp, Clin Med Coll 2, Dept Gastroenterol, Shenzhen 518020, Guangdong Provi, Peoples R China
4.Southern Univ Sci & Technol, Affiliated Hosp 1, Shenzhen 518020, Guangdong Provi, Peoples R China
5.Jinan Univ, Shenzhen Peoples Hosp, Clin Med Coll 2, Dept Gastroenterol, 1017 East Gate Rd, Shenzhen 518020, Guangdong Provi, Peoples R China
6.Southern Univ Sci & Technol, Affiliated Hosp 1, 1017 East Gate Rd, Shenzhen 518020, Guangdong Provi, Peoples R China

Huang, Jia-Lan,Gan, Ri-Yun,Chen, Ze-Han,et al. Endoscopic mucosal resection with double band ligation versus endoscopic submucosal dissection for small rectal neuroendocrine tumors[J]. WORLD JOURNAL OF GASTROINTESTINAL SURGERY,2023,15(3).

Huang, Jia-Lan.,Gan, Ri-Yun.,Chen, Ze-Han.,Gao, Ruo-Yu.,Li, De-Feng.,...&Yao, Jun.(2023).Endoscopic mucosal resection with double band ligation versus endoscopic submucosal dissection for small rectal neuroendocrine tumors.WORLD JOURNAL OF GASTROINTESTINAL SURGERY,15(3).

Huang, Jia-Lan,et al."Endoscopic mucosal resection with double band ligation versus endoscopic submucosal dissection for small rectal neuroendocrine tumors".WORLD JOURNAL OF GASTROINTESTINAL SURGERY 15.3(2023).