Short-term prognosis of very-preterm infants of ethnic minorities and Han nationality at high altitude: a single-center, retrospective study

He, Shengnan1; Shi, Yanling2; Wang, Fei2; Li, Cungui2; Kang, Jing2; Zhang, Guofei2; Zhou, Kanghua1; Yu, Zhangbin3; Yao, Yanli2,4; Peng, Haibo1,5

2023-12-15

10.1080/14767058.2023.2228455

JOURNAL OF MATERNAL-FETAL & NEONATAL MEDICINE   影响因子和分区

1476-7058

1476-4954

Objective We aimed to analyze the perinatal care of very-preterm infants (VPIs) in plateau areas of China and to explore any differences in short-term outcomes between ethnic minorities and Han nationality. Methods VPIs with gestational age (GA) <32 weeks admitted to Qinghai Red Cross Hospital from 1 January 2018 to 31 December 2020 were enrolled. Maternal information, neonatal information, perinatal care and discharge outcomes were retrospectively collected and analyzed. Results A total of 302 VPIs were examined, including 143 (47.4%) ethnic minority infants and 159 (52.6%) Han infants. Mothers of ethnic minority infants were significantly younger than those of Han infants (27 y vs. 30 y, p < .001). There were no differences in the incidence of assisted reproduction, multiple pregnancies, maternal hypertension, clinical chorioamnionitis or premature rupture of membranes >18 h between ethnic minority mothers and Han mothers. Lower proportions of cesarean section and incidence of maternal diabetes were observed in ethnic minority mothers than in Han mothers [(9.1 vs.17.6%, p < .05) and (42.7 vs. 57.9%, p < .05, respectively)]. Meanwhile, fewer antenatal steroids were used in minority group than Han group (65.7 vs. 81.1%, p < .05). No significant differences in rates of death, active treatment, necrotizing enterocolitis stage & GE;2, moderate-to-severe BPD, and incidence of severe retinopathy of prematurity in VPIs were found between the two groups and in all GA subgroups. Severe neurological injury was significantly less common in the minority newborns than in the Han infants (1.2 vs. 6.1%, p < .05). Compared with Han group, no excess risk of death, death or major morbidity, death despite active treatment, death or major morbidity despite active treatment was observed in ethnic minorities, with or without adjusting for gestational age and prenatal steroids. Conclusions Short-term prognosis of VPIs of ethnic minorities were similar to those of Han nationality.

Preterm infants ethnic minorities prognosis China

SCI

英语

其他

Obstetrics & Gynecology

Obstetrics & Gynecology

WOS:001015963300001

TAYLOR & FRANCIS LTD

Web of Science

1.Jinan Univ, Shenzhen Baoan Womens & Childrens Hosp, Dept Neonatol, Shenzhen, Peoples R China
2.Qinghai Red Cross Hosp, Dept Neonatol, Xining, Peoples R China
3.Southern Univ Sci & Technol, Shenzhen Peoples Hosp, Dept Neonatol, Affiliated Hosp 1, Shenzhen, Peoples R China
4.Qinghai Red Cross Hosp, Xining, Peoples R China
5.Jinan Univ, Shenzhen Baoan Womens & Childrens Hosp, Shenzhen, Peoples R China

He, Shengnan,Shi, Yanling,Wang, Fei,et al. Short-term prognosis of very-preterm infants of ethnic minorities and Han nationality at high altitude: a single-center, retrospective study[J]. JOURNAL OF MATERNAL-FETAL & NEONATAL MEDICINE,2023,36(2).

He, Shengnan.,Shi, Yanling.,Wang, Fei.,Li, Cungui.,Kang, Jing.,...&Peng, Haibo.(2023).Short-term prognosis of very-preterm infants of ethnic minorities and Han nationality at high altitude: a single-center, retrospective study.JOURNAL OF MATERNAL-FETAL & NEONATAL MEDICINE,36(2).

He, Shengnan,et al."Short-term prognosis of very-preterm infants of ethnic minorities and Han nationality at high altitude: a single-center, retrospective study".JOURNAL OF MATERNAL-FETAL & NEONATAL MEDICINE 36.2(2023).