Proton-Coupled Photochromic Hemithioindigo: Toward Photoactivated Chemical Sensing and Imaging

Li, Jing1; Ma, Xueqing1; Wang, Yifu1; Cheng, Yu1; Qin, Yuemin1; Zhai, Jingying2; Xie, Xiaojiang1

2023-07-01

10.1021/acs.analchem.3c01504

ANALYTICAL CHEMISTRY   影响因子和分区

0003-2700

1520-6882

We report photoswitchable fluorescent hemithioindigos(HTIs) wherethe metastable E isomers were stabilized by the proton-bridged intramolecularhydrogen bond. Titration experiments and computational analysis indicatedthat the E isomers were much more basic than the Z isomers, whichenabled photoactivated colorimetric and fluorescent pH response insolvents and polypropylene films. The HTIs exhibited reversibly switchablefluorescence with the Z isomers being the most fluorescent. Moreover,the HTIs were lysosomotropic and the kinetic fluorescence evolutionduring photoswitching was able to differentiate subcellular compartmentswith different pH. The combination of photoenhanced basicity, switchablefluorescence, and proton-coupled photochromism lay the groundworkfor a broad range of chemical and biological applications.

SCI ; EI

英语

NI论文

第一 ; 通讯

National Natural Science Foundation of China[22274070] ; Shenzhen Science and Technology Program[202110293000007] ; National Key Research and Development Program of China[2021YFA0715900]

Chemistry

Chemistry, Analytical

WOS:001034623000001

AMER CHEMICAL SOC

20233314562015

Alkalinity ; Chemical sensors ; Colorimetry ; Fluorescence ; Isomers ; Photochromism ; Plastic films ; Polypropylenes ; Titration

Light/Optics:741.1 ; Chemistry:801 ; Chemistry, General:801.1 ; Physical Chemistry:801.4 ; Chemical Products Generally:804 ; Organic Polymers:815.1.1 ; Polymer Products:817.1 ; Optical Variables Measurements:941.4

CHEMISTRY

Web of Science

1.Southern Univ Sci & Technol, Dept Chem, Shenzhen 518055, Peoples R China
2.Southern Univ Sci & Technol, Acad Adv Interdisciplinary Studies, Shenzhen 518055, Peoples R China

Li, Jing,Ma, Xueqing,Wang, Yifu,et al. Proton-Coupled Photochromic Hemithioindigo: Toward Photoactivated Chemical Sensing and Imaging[J]. ANALYTICAL CHEMISTRY,2023,95(31):11664-11671.

Li, Jing.,Ma, Xueqing.,Wang, Yifu.,Cheng, Yu.,Qin, Yuemin.,...&Xie, Xiaojiang.(2023).Proton-Coupled Photochromic Hemithioindigo: Toward Photoactivated Chemical Sensing and Imaging.ANALYTICAL CHEMISTRY,95(31),11664-11671.

Li, Jing,et al."Proton-Coupled Photochromic Hemithioindigo: Toward Photoactivated Chemical Sensing and Imaging".ANALYTICAL CHEMISTRY 95.31(2023):11664-11671.