南方科技大学知识苑(SUSTech KC): Analysis of Tumor Immune Microenvironment Based on Bulk RNA-sequencing Data and Its Application

题名	Analysis of Tumor Immune Microenvironment Based on Bulk RNA-sequencing Data and Its Application
作者	Chen，Xiao ; Liu，Quan; Ren，Huan
通讯作者	Ren，Huan
发表日期	2023
DOI	10.3971/j.issn.1000-8578.2023.22.1027
发表期刊	Cancer Research on Prevention and Treatment 影响因子和分区
ISSN	1000-8578
卷号	50 期号:5页码:458-462
摘要	Cancer immunotherapy is one of the most promising biological therapies. The dynamic changes of the immune microenvironment of heterogeneous tumors are critical factors in determining the interaction and therapeutic efficacy between tumor and immune microenvironment. Therefore, quantitative analysis of its constituent cells, related genes, and phenotypes in real time is of great importance. The methods used to analyze tumor immune microenvironment include immunohistochemistry, flow cytometry and so on. With the development of next-generation sequencing technology, transcriptome RNA sequencing data analysis has become one of the important methods to determine the composition of tumor immune microenvironment. This article focuses on the common methods of bulk RNA sequencing data analysis and related research progress.
关键词	Algorithmic tools Bulk transcriptome sequencing Deconvolution Immune microenvironment Immunotherapy Tumor
相关链接	[Scopus记录]
语种	英语
学校署名	第一 ; 通讯
资助项目	National Natural Science Foundation of China[81472367];National Natural Science Foundation of China[81871993];
Scopus记录号	2-s2.0-85163209275
来源库	Scopus
引用统计	被引频次[WOS]：0
成果类型	期刊论文
条目标识符	http://sustech.caswiz.com/handle/2SGJ60CL/560266
专题	南方科技大学医学院
作者单位	School of Medicine,Southern University of Science and Technology,Shenzhen,518055,China
第一作者单位	南方科技大学医学院
通讯作者单位	南方科技大学医学院
第一作者的第一单位	南方科技大学医学院
推荐引用方式 GB/T 7714	Chen，Xiao,Liu，Quan,Ren，Huan. Analysis of Tumor Immune Microenvironment Based on Bulk RNA-sequencing Data and Its Application[J]. Cancer Research on Prevention and Treatment,2023,50(5):458-462.
APA	Chen，Xiao,Liu，Quan,&Ren，Huan.(2023).Analysis of Tumor Immune Microenvironment Based on Bulk RNA-sequencing Data and Its Application.Cancer Research on Prevention and Treatment,50(5),458-462.
MLA	Chen，Xiao,et al."Analysis of Tumor Immune Microenvironment Based on Bulk RNA-sequencing Data and Its Application".Cancer Research on Prevention and Treatment 50.5(2023):458-462.