南方科技大学知识苑(SUSTech KC): Case report: PRES associated with fruquintinib in a patient with metastatic colon cancer

题名	Case report: PRES associated with fruquintinib in a patient with metastatic colon cancer
作者	Wang, Lu 1; Zeng, Zhaohao 2; Wu, Zhiqiang 1
通讯作者	Wu, Zhiqiang
发表日期	2023-08-01
DOI	10.1007/s10072-023-06991-7
发表期刊	NEUROLOGICAL SCIENCES 影响因子和分区
ISSN	1590-1874
EISSN	1590-3478
卷号	44 期号:11
摘要	Posterior reversible encephalopathy syndrome (PRES) is a rare, reversible neurological disease that is frequently associated with the use of targeted therapy agents. In this case study, we examine the development of posterior reversible encephalopathy syndrome (PRES) in a 44-year-old woman with metastatic colon cancer following 1 month of treatment with the vascular endothelial growth factor receptor (VEGFR) inhibitor, fruquintinib. The occurrence of PRES after 1 month of VEGFR inhibitor administration is a common phenomenon. However, it is noteworthy that this is the first reported case of PRES associated with fruquintinib. The patient's neurological function improved upon discontinuing the drug for a week, but worsening was observed following a lower-dose fruquintinib treatment. This patient's experience highlights the potential for neurological deterioration in those treated with fruquintinib, prompting physicians to consider the possibility of PRES. Notably, this may be the first reported case linking fruquintinib to the syndrome, underscoring the importance of recognizing the association between PRES and fruquintinib.
关键词	Posterior reversible encephalopathy syndrome (PRES) Fruquintinib Metastatic colon cancer
相关链接	[来源记录]
收录类别	SCI
语种	英语
学校署名	其他
WOS研究方向	Neurosciences & Neurology
WOS类目	Clinical Neurology ; Neurosciences
WOS记录号	WOS:001049066000002
出版者	SPRINGER-VERLAG ITALIA SRL
ESI学科分类	NEUROSCIENCE & BEHAVIOR
来源库	Web of Science
引用统计	被引频次[WOS]：1
成果类型	期刊论文
条目标识符	http://sustech.caswiz.com/handle/2SGJ60CL/583024
专题	南方科技大学第一附属医院
作者单位	1.Wuhan Univ Sci & Technol, Xiaogan Hosp, Dept Neurol, Xiaogan, Hubei, Peoples R China 2.Southern Univ Sci & Technol, Jinan Univ, Shenzhen Peoples Hosp, Affiliated Hosp 1,Dept Neurol,Clin Med Coll 2, Shenzhen 518001, Guangdong, Peoples R China
推荐引用方式 GB/T 7714	Wang, Lu,Zeng, Zhaohao,Wu, Zhiqiang. Case report: PRES associated with fruquintinib in a patient with metastatic colon cancer[J]. NEUROLOGICAL SCIENCES,2023,44(11).
APA	Wang, Lu,Zeng, Zhaohao,&Wu, Zhiqiang.(2023).Case report: PRES associated with fruquintinib in a patient with metastatic colon cancer.NEUROLOGICAL SCIENCES,44(11).
MLA	Wang, Lu,et al."Case report: PRES associated with fruquintinib in a patient with metastatic colon cancer".NEUROLOGICAL SCIENCES 44.11(2023).