南方科技大学知识苑(SUSTech KC): ANALYSIS OF MULTIPLE ORGAN FUNCTION DAMAGE IN PATIENTS WITH SEVERE COVID-19 PNEUMONIA

题名	ANALYSIS OF MULTIPLE ORGAN FUNCTION DAMAGE IN PATIENTS WITH SEVERE COVID-19 PNEUMONIA
作者	Feng, Shiyan; Wang, Fengxin; Wu, Weibo; Li, Yinfeng; Chen, Chuming; Li, Jianming; Cao, Mengli; Peng, Ling; Zhang, Peiyan; Wang, Fuxiang
通讯作者	Wang, Fuxiang
发表日期	2023
DOI	10.5937/jomb0-41502
发表期刊	JOURNAL OF MEDICAL BIOCHEMISTRY 影响因子和分区
ISSN	1452-8258
EISSN	1452-8266
卷号	42 期号:3
摘要	Background: This study aims to analyze the changes and significance of organ function indices in patients with severe Coronavirus Disease 2019 (COVID-19) pneumonia for prediction of major organ damages and guiding treatment schemes. Methods: 63 patients with severe COVID-19 pneumonia were selected as the severe group and 73 patients with mild syndromes were selected as the mild group. SAS9.4 software was used for statistical analysis of the data. Results: Levels of ALT, AST, cTnI, Cr, PT, APTT and Ddimer of the severe group were significantly higher while PLT was lower than those of the mild group. The data of all quantitative variables were converted into categorical variables. Significantly higher levels of AST, ALB, D-dimer and higher proportion of bilateral lung involvement were observed from the severe group comparing to those in the mild group, while the difference in the other indices between the two groups was insignificant in statistical perspective. Conclusions: There are significant differences in the levels of multiple organ function indices between the severe group and the mild group of patients with COVID-19 pneumonia infection. Through examining the relevant indices, conditions of patients' multiple organ function damage could be predicted and used as guidance of treatment.
关键词	severe cases coronavirus disease 2019 (COVID-19) pneumonia organ function index
相关链接	[来源记录]
收录类别	SCI
语种	英语
学校署名	第一 ; 通讯
资助项目	Natural Science Foundation of China[81672003] ; National Science and Technology Major Project[2017ZX10103011]
WOS研究方向	Biochemistry & Molecular Biology
WOS类目	Biochemistry & Molecular Biology
WOS记录号	WOS:001044436200013
出版者	SOC MEDICAL BIOCHEMISTS SERBIA
来源库	Web of Science
引用统计
成果类型	期刊论文
条目标识符	http://sustech.caswiz.com/handle/2SGJ60CL/583035
专题	南方科技大学第二附属医院南方科技大学第一附属医院
作者单位	Southern Univ Sci & Technol, Shenzhen Peoples Hosp 3, Hosp 2, Shenzhen 518000, Guangdong, Peoples R China
第一作者单位	南方科技大学第二附属医院; 南方科技大学第一附属医院
通讯作者单位	南方科技大学第二附属医院; 南方科技大学第一附属医院
第一作者的第一单位	南方科技大学第二附属医院; 南方科技大学第一附属医院
推荐引用方式 GB/T 7714	Feng, Shiyan,Wang, Fengxin,Wu, Weibo,et al. ANALYSIS OF MULTIPLE ORGAN FUNCTION DAMAGE IN PATIENTS WITH SEVERE COVID-19 PNEUMONIA[J]. JOURNAL OF MEDICAL BIOCHEMISTRY,2023,42(3).
APA	Feng, Shiyan.,Wang, Fengxin.,Wu, Weibo.,Li, Yinfeng.,Chen, Chuming.,...&Wang, Fuxiang.(2023).ANALYSIS OF MULTIPLE ORGAN FUNCTION DAMAGE IN PATIENTS WITH SEVERE COVID-19 PNEUMONIA.JOURNAL OF MEDICAL BIOCHEMISTRY,42(3).
MLA	Feng, Shiyan,et al."ANALYSIS OF MULTIPLE ORGAN FUNCTION DAMAGE IN PATIENTS WITH SEVERE COVID-19 PNEUMONIA".JOURNAL OF MEDICAL BIOCHEMISTRY 42.3(2023).