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题名

Biological behavior of the extract of green walnut husks on gastric cancer MGC80-3 cells

作者
通讯作者Gao, Junfeng; Guo, Hong
发表日期
2023-05-01
DOI
发表期刊
ISSN
2158-5849
EISSN
2158-5857
卷号13期号:5
摘要
Stomach cancer (SC) is a relatively common cancer in my country, with a high mortality rate, which seriously threatens our health. This article studied the effect of Green walnut husks (GWH) extract on the biological IP: 203.8.109.20 On: Wed, 12 Jul 2023 07:01 29 behaviors and NF-KB protein levels of gastric cancer MGC80-3 cells, and provided evidence and support for Copyright: American Scientific Pub shers the research and treatment of gastric cancer. Cell proliferation was measured by Thiazole blue and apoptosis Delivered by Ingenta by flow cytometry. Cell migration was analyzed by scratch experiment and the levels of NF-KB, NF-KBp65 and COX-2 in MGC80-3 cells were examined by Western blot and QRC-PCR. It was found that GWH extract inhib-ited cell proliferation and increased apoptosis. GWH extract significantly downregulated NF-KB, NF-KBp65 and COX-2. The growth process of cancer cells is related to biological behaviors such as cell proliferation and apoptosis. By inhibiting the biological behavior of cancer cells, inhibitory proteins can effectively inhibit gastric cancer. In summary, GWH extract has a great influence on gastric cancer MGC80-3 cells and the NF-KB protein expression.
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收录类别
语种
英语
学校署名
通讯
WOS研究方向
Science & Technology - Other Topics ; Materials Science
WOS类目
Nanoscience & Nanotechnology ; Materials Science, Multidisciplinary
WOS记录号
WOS:001030641900002
出版者
来源库
Web of Science
引用统计
被引频次[WOS]:1
成果类型期刊论文
条目标识符http://sustech.caswiz.com/handle/2SGJ60CL/583052
专题南方科技大学
作者单位
1.Huludao Cent Hosp, Tumor Day Ward, Huludao 125000, Liaoning, Peoples R China
2.Southern Univ Sci, Technol Yantian Hosp, Dept Emergency, Shenzhen 518000, Guangdong, Peoples R China
3.Strateg Support Force Med Ctr, Dept Med, Beijing 100000, Peoples R China
4.Steel Grp Gen Hosp, Dept Gen Surg, Anshan 114000, Liaoning, Peoples R China
5.Southern Univ Sci & Technol, Yantian Hosp, Dept Lab Med, Shenzhen 518000, Guangdong, Peoples R China
通讯作者单位南方科技大学
推荐引用方式
GB/T 7714
Li, Jing,Wang, Weiguang,Li, Baowei,et al. Biological behavior of the extract of green walnut husks on gastric cancer MGC80-3 cells[J]. MATERIALS EXPRESS,2023,13(5).
APA
Li, Jing,Wang, Weiguang,Li, Baowei,Wu, Guogang,Gao, Junfeng,&Guo, Hong.(2023).Biological behavior of the extract of green walnut husks on gastric cancer MGC80-3 cells.MATERIALS EXPRESS,13(5).
MLA
Li, Jing,et al."Biological behavior of the extract of green walnut husks on gastric cancer MGC80-3 cells".MATERIALS EXPRESS 13.5(2023).
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