| 题名 | Noncancerous disease-targeting AIEgens |
| 作者 | |
| 通讯作者 | Duo, Yanhong; Luo, Guanghong; Yoon, Juyoung; Tang, Ben Zhong |
| 发表日期 | 2023-02-06
|
| DOI | |
| 发表期刊 | |
| ISSN | 0306-0012
|
| EISSN | 1460-4744
|
| 卷号 | 52期号:3 |
| 摘要 | Noncancerous diseases include a wide plethora of medical conditions beyond cancer and are a major cause of mortality around the world. Despite progresses in clinical research, many puzzles about these diseases remain unanswered, and new therapies are continuously being sought. The evolution of bio-nanomedicine has enabled huge advancements in biosensing, diagnosis, bioimaging, and therapeutics. The recent development of aggregation-induced emission luminogens (AIEgens) has provided an impetus to the field of molecular bionanomaterials. Following aggregation, AIEgens show strong emission, overcoming the problems associated with the aggregation-caused quenching (ACQ) effect. They also have other unique properties, including low background interferences, high signal-to-noise ratios, photostability, and excellent biocompatibility, along with activatable aggregation-enhanced theranostic effects, which help them achieve excellent therapeutic effects as an one-for-all multimodal theranostic platform. This review provides a comprehensive overview of the overall progresses in AIEgen-based nanoplatforms for the detection, diagnosis, bioimaging, and bioimaging-guided treatment of noncancerous diseases. In addition, it details future perspectives and the potential clinical applications of these AIEgens in noncancerous diseases are also proposed. This review hopes to motivate further interest in this topic and promote ideation for the further exploration of more advanced AIEgens in a broad range of biomedical and clinical applications in patients with noncancerous diseases. |
| 相关链接 | [来源记录] |
| 收录类别 | |
| 语种 | 英语
|
| 重要成果 | ESI高被引
|
| 学校署名 | 第一
; 通讯
|
| 资助项目 | null[82102904]
; null[JCYJ20190807144605514]
; null[JCYJ20210324113405014]
; null[JCYJ20190808154213097]
; null[2021R1A6A1A10039823]
|
| WOS研究方向 | Chemistry
|
| WOS类目 | Chemistry, Multidisciplinary
|
| WOS记录号 | WOS:000907711700001
|
| 出版者 | |
| ESI学科分类 | CHEMISTRY
|
| 来源库 | Web of Science
|
| 引用统计 |
被引频次[WOS]：42
|
| 成果类型 | 期刊论文 |
| 条目标识符 | http://sustech.caswiz.com/handle/2SGJ60CL/583160 |
| 专题 | 南方科技大学第一附属医院 |
| 作者单位 | 1.Jinan Univ, Southern Univ Sci & Technol, Shenzhen Peoples Hosp, Affiliated Hosp 1,Dept Radiat Oncol,Clin Med Col, Shenzhen 518020, Guangdong, Peoples R China 2.Karolinska Inst, Dept Microbiol, Tumor & Cell Biol MTC, Stockholm, Sweden 3.Dalian Univ Technol, Sch Chem Engn, Dept Pharmacol, State Key Lab Fine Chem, Dalian, Peoples R China 4.Ewha Womans Univ, Dept Chem & Nanosci, 52 Ewhayeodae Gil, Seoul 03760, South Korea 5.Chinese Univ Hong Kong, Shenzhen Inst Aggregate Sci & Technol, Sch Sci & Engn, Shenzhen 518172, Guangdong, Peoples R China 6.Sun Yat Sen Univ, Affiliated Hosp 8, Dept Orthoped, Shenzhen 518033, Guangdong, Peoples R China 7.Chinese Univ Hong Kong, Sch Med, Life & Hlth Sci, Shenzhen 518172, Guangdong, Peoples R China |
| 第一作者单位 | 南方科技大学第一附属医院 |
| 通讯作者单位 | 南方科技大学第一附属医院 |
| 第一作者的第一单位 | 南方科技大学第一附属医院 |
| 推荐引用方式 GB/T 7714 |
Duo, Yanhong,Luo, Guanghong,Zhang, Wentao,et al. Noncancerous disease-targeting AIEgens[J]. CHEMICAL SOCIETY REVIEWS,2023,52(3).
|
| APA |
Duo, Yanhong.,Luo, Guanghong.,Zhang, Wentao.,Wang, Renzhi.,Xiao, Gary Guishan.,...&Tang, Ben Zhong.(2023).Noncancerous disease-targeting AIEgens.CHEMICAL SOCIETY REVIEWS,52(3).
|
| MLA |
Duo, Yanhong,et al."Noncancerous disease-targeting AIEgens".CHEMICAL SOCIETY REVIEWS 52.3(2023).
|
| 条目包含的文件 | 条目无相关文件。 | |||||
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。
;
修改评论