南方科技大学知识苑(SUSTech KC): Mitochondrial disorders as a mechanism for the development of obese Sarcopenia

题名	Mitochondrial disorders as a mechanism for the development of obese Sarcopenia
作者	Liao，Tingfeng1,2,3 ; Xiong，Lijiao 2,3; Wang，Xiaohao1,2,3 ; Yang，Shu 1,2; Liang，Zhen 1,2
通讯作者	Yang，Shu
发表日期	2023-12-01
DOI	10.1186/s13098-023-01192-w
发表期刊	Diabetology and Metabolic Syndrome 影响因子和分区
EISSN	1758-5996
卷号	15 期号:1
摘要	Obese sarcopenia is a severe and prevalent disease in an aging society. Compared to sarcopenia alone, the development and advanced stage of obesity sarcopenia is faster and more severe. Diagnosis of the cause of adipocyte accumulation is also more complicated; however, no effective pharmacological treatment is available. Chronic inflammation is one of the causes of sarcopenia, and obese patients, who are more likely to develop chronic inflammation, may simultaneously suffer from obesity and sarcopenia. Mitochondrial metabolic disorders have been more easily observed in the tissue cells of patients with obesity and sarcopenia. Mitochondrial metabolic disorders include abnormal mtDNA release, mitochondrial autophagy, and dynamic mitochondrial disorders. Therefore, this review will reveal the mechanism of development of obesity myasthenia gravis from the perspective of mitochondria and discuss the currently existing small-molecule drugs.
相关链接	[Scopus记录]
收录类别	SCI
语种	英语
学校署名	第一 ; 通讯
WOS记录号	WOS:001098757800002
Scopus记录号	2-s2.0-85175798136
来源库	Scopus
引用统计
成果类型	期刊论文
条目标识符	http://sustech.caswiz.com/handle/2SGJ60CL/602247
专题	南方科技大学医学院南方科技大学第一附属医院
作者单位	1.School of Medicine,The First Affiliated Hospital of Southern University of Science and Technology,Shenzhen People’s Hospital (The Second Clinical Medical College,Jinan University),Shenzhen,China 2.Department of Geriatrics,Shenzhen People’s Hospital,(The Second Clinical Medical College,Jinan University,The First Affiliated Hospital,Southern University of Science and Technology,Shenzhen,China 3.Shenzhen Clinical Research Centre for Geriatrics,Shenzhen People’s Hospital,Shenzhen,China
第一作者单位	南方科技大学医学院; 南方科技大学第一附属医院
通讯作者单位	南方科技大学医学院; 南方科技大学第一附属医院
第一作者的第一单位	南方科技大学医学院; 南方科技大学第一附属医院
推荐引用方式 GB/T 7714	Liao，Tingfeng,Xiong，Lijiao,Wang，Xiaohao,et al. Mitochondrial disorders as a mechanism for the development of obese Sarcopenia[J]. Diabetology and Metabolic Syndrome,2023,15(1).
APA	Liao，Tingfeng,Xiong，Lijiao,Wang，Xiaohao,Yang，Shu,&Liang，Zhen.(2023).Mitochondrial disorders as a mechanism for the development of obese Sarcopenia.Diabetology and Metabolic Syndrome,15(1).
MLA	Liao，Tingfeng,et al."Mitochondrial disorders as a mechanism for the development of obese Sarcopenia".Diabetology and Metabolic Syndrome 15.1(2023).