Impacts of short-term low-level exposure to air pollutants on hospital admissions for pulmonary sepsis in elderly patients

Chen, Jing1,2; Liu, Aiming3; Dai, Junjie2,4; Li, Yichen1,2; Zhang, Yu1,2; Chen, Rongchang2,4; Shi, Fei2,5

2023-11-17

10.1186/s12890-023-02652-9

BMC PULMONARY MEDICINE   影响因子和分区

1471-2466

["Background Acute exposures to high levels of air pollutants are thought to be associated with hospitalization of patients with lung infection, while relatively little is known about the association between air pollutants and HOSPITAL ADMISSIONS FOR pulmonary sepsis.","Objectives To assess the correlation between low-level exposure to air pollutants and the hospitalizations for pulmonary sepsis in elderly patients.","Methods A total of 249 elderly patients with pulmonary sepsis from January 2018 to December 2020 in Shenzhen people's hospital were included. The data regarding hospitalizations for pulmonary sepsis, meteorological factors, and daily average levels of air pollutants on single-day lags (Lag0 to Lag7) in Shenzhen were collected. Low-level exposure was defined as the annual means of air pollutants below the levels of the Ambient Air Quality Standard (AAQS) in China (NO. GB3095-2012) and/or Global Air Quality Guidelines (AQG). A time-stratified case-crossover study design approach was used to evaluate the associations between exposure to air pollutants and incidence of the disease, univariate and multivariate logistic regression analysis to analyze the association between levels of air pollutants and hospitalizations for pulmonary sepsis in elderly patients.","Results Exposure to PM1(P = 0.007, Lag 2 day; P = 0.038, Lag6 day), PM2.5(P = 0.046, Lag2 day), PM10(P = 0.048, Lag4 day), and O-3(P = 0.044, Lag6 day) was positively correlated with elevated risk of hospitalizations for pulmonary sepsis. In addition, logistic regression analysis revealed that exposure to PM1 (OR = 1.833, 95%CI:1.032 similar to 3.256, Lag6 day) and O-3 (OR = 2.091, 95%CI:1.019 similar to 4.289, Lag6 day) were the independent risk factors of pulmonary sepsis in elderly patients.","Conclusion Our results demonstrate that short-term low-level exposure to PM1 and O-3 could elevate the risk of hospitalizations for pulmonary sepsis in elderly patients in Shenzhen, providing evidence for developing early warning and screening systems for pulmonary sepsis."]

Low-level exposure Air pollutants Pulmonary sepsis Elderly Lag-effect

SCI

英语

通讯

Respiratory System

Respiratory System

WOS:001106637700003

BMC

Web of Science

1.Jinan Univ, Shenzhen Peoples Hosp, Emergency Dept, 2 Clin Med Coll, Shenzhen 518020, Guangdong, Peoples R China
2.Southern Univ Sci & Technol, Affiliated Hosp 1, Shenzhen 518020, Guangdong, Peoples R China
3.Meteorol Bur Shenzhen Municipal, Shenzhen Natl Climate Observ, Shenzhen, Guangdong, Peoples R China
4.Jinan Univ, Shenzhen Peoples Hosp, Inst Shenzhen Resp Dis, Key Lab Shenzhen Resp Dis,2 Clin Med Coll, Shenzhen 518020, Guangdong, Peoples R China
5.Jinan Univ, Shenzhen Peoples Hosp, Inst Shenzhen Resp Dis, Dept Infect Dis,2 Clin Med Coll, Shenzhen 518020, Guangdong, Peoples R China

Chen, Jing,Liu, Aiming,Dai, Junjie,et al. Impacts of short-term low-level exposure to air pollutants on hospital admissions for pulmonary sepsis in elderly patients[J]. BMC PULMONARY MEDICINE,2023,23(1).

Chen, Jing.,Liu, Aiming.,Dai, Junjie.,Li, Yichen.,Zhang, Yu.,...&Shi, Fei.(2023).Impacts of short-term low-level exposure to air pollutants on hospital admissions for pulmonary sepsis in elderly patients.BMC PULMONARY MEDICINE,23(1).

Chen, Jing,et al."Impacts of short-term low-level exposure to air pollutants on hospital admissions for pulmonary sepsis in elderly patients".BMC PULMONARY MEDICINE 23.1(2023).