Liquid-liquid phase separation as a major mechanism of plant abiotic stress sensing and responses

Liu，Xin1; Zhu，Jian Kang2,3; Zhao，Chunzhao1

2023-12-01

10.1007/s44154-023-00141-x

Stress Biology   影响因子和分区

2731-0450

Identification of environmental stress sensors is one of the most important research topics in plant abiotic stress research. Traditional strategies to identify stress sensors or early signaling components based on the cell membrane as a primary site of sensing and calcium signal as a second messenger have had only limited successes. Therefore, the current theoretical framework underlying stress sensing in plants should be reconsidered and additional mechanisms need to be introduced. Recently, accumulating evidence has emerged to suggest that liquid-liquid phase separation (LLPS) is a major mechanism for environmental stress sensing and response in plants. In this review, we briefly introduce LLPS regarding its concept, compositions, and dynamics, and then summarize recent progress of LLPS research in plants, emphasizing the contribution of LLPS to the sensing of various environmental stresses, such as dehydration, osmotic stress, and low and high temperatures. Finally, we propose strategies to identify key proteins that sense and respond to environmental stimuli on the basis of LLPS, and discuss the research directions of LLPS in plant abiotic stress responses and its potential application in enhancing stress tolerance in crops.

Biomolecular condensates High temperature Liquid-liquid phase separation Osmotic stress Stress sensors

英语

其他

2-s2.0-85179324591

Scopus

1.Shanghai Center for Plant Stress Biology,CAS Center for Excellence in Molecular Plant Sciences,Chinese Academy of Sciences,Shanghai,China
2.Institute of Advanced Biotechnology and School of Life Sciences,Southern University of Science and Technology,Shenzhen,China
3.Center for Advanced Bioindustry Technologies,Chinese Academy of Agricultural Sciences,Beijing,China

Liu，Xin,Zhu，Jian Kang,Zhao，Chunzhao. Liquid-liquid phase separation as a major mechanism of plant abiotic stress sensing and responses[J]. Stress Biology,2023,3(1).

Liu，Xin,Zhu，Jian Kang,&Zhao，Chunzhao.(2023).Liquid-liquid phase separation as a major mechanism of plant abiotic stress sensing and responses.Stress Biology,3(1).

Liu，Xin,et al."Liquid-liquid phase separation as a major mechanism of plant abiotic stress sensing and responses".Stress Biology 3.1(2023).