Integrative metabolome and transcriptome analyses reveal the differences in flavonoid and terpenoid synthesis between Glycyrrhiza uralensis (licorice) leaves and roots

Yu，Kaiqiang1,2,4; Peng，Li1,3; Liang，Wenyu1,3; Shi，Jing1,3; Zheng，Guoqi1,3; Wang，Hong2; Liang，Xinhua1,3; Wu，Shijie2

2024

10.1007/s10068-023-01467-y

Food Science and Biotechnology   影响因子和分区

1226-7708

2092-6456

Licorice from Glycyrrhiza uralensis roots is used in foods and medicines. Although we are aware that licorice roots and leaves have distinct material compositions, the specific reasons for these differences remain unknown. Comparison of the metabolomes and transcriptomes between the leaves and roots revealed flavonoids and triterpenoid saponins were significantly different. Isoflavones were enriched in roots because of upregulation of genes encoding chalcone isomerase and flavone synthase, which are involved in isoflavone synthesis. Six triterpenoid saponins were significantly enriched only in the roots. The leaves did not accumulate glycyrrhetinic acid because of low expression levels of genes involved in its synthesis. A gene encoding a UDP glycosyltransferase, which likely catalyzes the key step in the transformation of glycyrrhetinic acid to glycyrrhizin, was screened. Our results provide information about the differences in flavonoid and triterpenoid synthesis between roots and leaves, and highlight targets for genetic engineering.

Flavonoids Glycyrrhiza uralensis (Licorice) Metabolomic Transcriptomic Triterpenoid

SCI ; EI

英语

其他

AGRICULTURAL SCIENCES

2-s2.0-85177023323

Scopus

1.School of Life Sciences,Ningxia University,Yinchuan,750021,China
2.School of Resource,Environment and Life Science,Ningxia Normal University,Guyuan,756000,China
3.Key Lab of Ministry of Education for Protection and Utilization of Special Biological,Resources in Western China,Ningxia University,Yinchuan,750021,China
4.School of Environmental Science and Engineering,Southern University of Science and Technology,Shenzhen,518055,China

Yu，Kaiqiang,Peng，Li,Liang，Wenyu,et al. Integrative metabolome and transcriptome analyses reveal the differences in flavonoid and terpenoid synthesis between Glycyrrhiza uralensis (licorice) leaves and roots[J]. Food Science and Biotechnology,2024,33(1):91-101.

Yu，Kaiqiang.,Peng，Li.,Liang，Wenyu.,Shi，Jing.,Zheng，Guoqi.,...&Wu，Shijie.(2024).Integrative metabolome and transcriptome analyses reveal the differences in flavonoid and terpenoid synthesis between Glycyrrhiza uralensis (licorice) leaves and roots.Food Science and Biotechnology,33(1),91-101.

Yu，Kaiqiang,et al."Integrative metabolome and transcriptome analyses reveal the differences in flavonoid and terpenoid synthesis between Glycyrrhiza uralensis (licorice) leaves and roots".Food Science and Biotechnology 33.1(2024):91-101.