A MEMS-based opto-acoustic-fluidic system for cell imaging

Wang，Min1; Jin，Tian2; Liu，Fei1; Chen，Xingxing1; Xi，Lei2

10.1117/12.2548901

2019

0277-786X

1996-756X

Proceedings of SPIE - The International Society for Optical Engineering

11209

Xi'an, China

1000 20TH ST, PO BOX 10, BELLINGHAM, WA 98227-0010 USA

SPIE

In this work, we employed a micro-electro-mechanical system (MEMS) mirror as the scanner to reduce the size of the opto-acuostic-fludic system. To evaluate the performance of this system, we imaged flowing droplets generated by Tjunction and flow focusing configurations. The results demonstrate the feasibility of this method in the study of droplet formation dynamics. We also imaged flowing magnetic microspheres to verify the influence of magnetic field. In the end, cancer cells were successfully detected in the microchannel to demonstrate the potential of this method in clinical applications.

cancer cell MEMS opto-acuostic-fludic

其他

英语

EI ; CPCI-S

Optics

Optics

WOS:000526177700127

20200508093059

Cells ; Diseases ; Drop formation ; Photonics

Biological Materials and Tissue Engineering:461.2 ; Electric Equipment:704.2 ; Light/Optics:741.1 ; Physical Properties of Gases, Liquids and Solids:931.2

2-s2.0-85078347272

Scopus

1.School of Electronic Science and Engineering,University of Electronic Science and Technology of China,Chengdu, Sichuan,610054,China
2.Department of Biomedical Engineering,Southern University of Science and Technology,Shenzhen, Guangdong,518055,China

Wang，Min,Jin，Tian,Liu，Fei,et al. A MEMS-based opto-acoustic-fluidic system for cell imaging[C]. 1000 20TH ST, PO BOX 10, BELLINGHAM, WA 98227-0010 USA:SPIE,2019.