Photoredox/nickel dual-catalysis-enabled synthesis of N-heterocycles from alkyl chlorides and alkenes

Yang，Xuege1; Shi，Lou1; Qin，Ruoyu1; Tao，Minglin1; Feng，Qin1; Chang，Xiao Yong3; Chang，Qiaowen2; Liang，Deqiang1

2024-01-15

10.1016/j.mcat.2023.113806

Molecular Catalysis   影响因子和分区

2468-8231

A photoredox/nickel dual catalysis is presented for the construction of several kinds of useful nitrogen-containing heterocycles. This protocol is regioselective and features a broad substrate scope. It provides a direct access to nitrogen-containing heterocycles by reacting alkyl chlorides with readily available activated and unactivated alkenes. Moreover, this protocol can be easily scalable to a gram-scale, and it is feasible to use sunlight as the light source. Mechanistic studies suggest that the energy transfer pathway is involved in the catalytic process.

Alkyl chlorides Energy transfer Nitrogen-containing heterocycles Photoredox/nickel dual catalysis Regioselective

SCI ; EI

英语

其他

2-s2.0-85181801083

Scopus

1.Yunnan Key Laboratory of Metal-Organic Molecular Materials and Device,School of Chemistry and Chemical Engineering,Kunming University,Kunming,2 Puxin Road,650214,China
2.State Key Laboratory of Advanced Technologies for Comprehensive Utilization of Platinum Metals,Kunming Institute of Precious Metals,Kunming,988 Keji Road,650106,China
3.Shenzhen Grubbs Institute and Department of Chemistry,Southern University of Science and Technology,Shenzhen,Guangdong,518055,China

Yang，Xuege,Shi，Lou,Qin，Ruoyu,et al. Photoredox/nickel dual-catalysis-enabled synthesis of N-heterocycles from alkyl chlorides and alkenes[J]. Molecular Catalysis,2024,553.

Yang，Xuege.,Shi，Lou.,Qin，Ruoyu.,Tao，Minglin.,Feng，Qin.,...&Liang，Deqiang.(2024).Photoredox/nickel dual-catalysis-enabled synthesis of N-heterocycles from alkyl chlorides and alkenes.Molecular Catalysis,553.

Yang，Xuege,et al."Photoredox/nickel dual-catalysis-enabled synthesis of N-heterocycles from alkyl chlorides and alkenes".Molecular Catalysis 553(2024).