南方科技大学知识苑(SUSTech KC): Association Between a History of Breast Cancer and Decreased Thyroid Cancer-specific Mortality

题名	Association Between a History of Breast Cancer and Decreased Thyroid Cancer-specific Mortality
作者	Lin, Shuhuang 1 ; Wang, Zhuo1 ; Xing, Mingzhao1,2
通讯作者	Xing, Mingzhao
发表日期	2023-12-01
DOI	10.1210/clinem/dgad722
发表期刊	JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM 影响因子和分区
ISSN	0021-972X
EISSN	1945-7197
摘要	Context: The clinical relevance of the well-known association between thyroid cancer (TC) and breast cancer (BC) remains to be further defined.Objective: This work aimed to investigate the effect of history of BC on the prognosis of TC.Methods: This was a comparative cohort study of tumor behaviors and TC-specific mortality in 5598 patients with papillary thyroid cancer (PTC) and 604 patients with follicular thyroid cancer (FTC), all with a history of BC (TC-BC patients), and their propensity score-matched TC patients without a history of BC (TCnoBC patients) in Surveillance, Epidemiology and End Results (SEER) 18. The main outcome measure was TC-specific mortality.Results: Lower TC distant metastasis rates of 2.4% vs 3.0% in PTC and 6.1% vs 9.1% in FTC and TC-specific mortality rates of 1.3% vs 2.6% in PTC and 5.8% vs 8.4% in FTC were found in TC-BC patients vs matched TCnoBC patients (all P < .05). Comparing TC-BC patients with matched TCnoBC patients, hazard ratios (HRs) for mortality were 0.472 (95% CI, 0.370-0.601) in PTC and 0.656 (95% CI, 0.461-0.934) in FTC (all P < .05). Such HRs for mortality in PTC were 0.397 (95% CI, 0.268-0.588; P < .001) when TC occurred before BC vs 0.607 (95% CI, 0.445-0.827; P = .002) when BC occurred before TC.Conclusion: This study demonstrates a robust protective effect of a history of BC on TC-specific patient survival, which has strong implications for more precise prognostication of TC in such patients.
关键词	thyroid cancer breast cancer mortality prognosis
相关链接	[来源记录]
收录类别	SCI
语种	英语
重要成果	NI论文
学校署名	第一 ; 通讯
资助项目	Special Fund Project for Science and Technology Innovation Strategy of Guangdong Province[pdjh2021b0440]
WOS研究方向	Endocrinology & Metabolism
WOS类目	Endocrinology & Metabolism
WOS记录号	WOS:001127616200001
出版者	ENDOCRINE SOC
ESI学科分类	CLINICAL MEDICINE
来源库	Web of Science
引用统计
成果类型	期刊论文
条目标识符	http://sustech.caswiz.com/handle/2SGJ60CL/729242
专题	南方科技大学医学院
作者单位	1.Southern Univ Sci & Technol, Thyroid Res Inst, Sch Med, Shenzhen 518055, Guangdong, Peoples R China 2.Southern Univ Sci & Technol, Thyroid Res Inst, Sch Med, 1088 Xueyuan Ave, Shenzhen 518055, Guangdong, Peoples R China
第一作者单位	南方科技大学医学院
通讯作者单位	南方科技大学医学院
第一作者的第一单位	南方科技大学医学院
推荐引用方式 GB/T 7714	Lin, Shuhuang,Wang, Zhuo,Xing, Mingzhao. Association Between a History of Breast Cancer and Decreased Thyroid Cancer-specific Mortality[J]. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM,2023.
APA	Lin, Shuhuang,Wang, Zhuo,&Xing, Mingzhao.(2023).Association Between a History of Breast Cancer and Decreased Thyroid Cancer-specific Mortality.JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM.
MLA	Lin, Shuhuang,et al."Association Between a History of Breast Cancer and Decreased Thyroid Cancer-specific Mortality".JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2023).