南方科技大学知识苑(SUSTech KC): Rhodium-Catalyzed Enantioselective Anti-Markovnikov Hydroformylation of α-Substituted Acryl Acid Derivatives

题名	Rhodium-Catalyzed Enantioselective Anti-Markovnikov Hydroformylation of α-Substituted Acryl Acid Derivatives
作者	Li，Shuailong 1; Li，Zhuangxing 1; You，Cai 1; Li，Xiuxiu 1; Yang，Jiaxin 1; Lv，Hui 1; Zhang，Xumu2
通讯作者	Lv，Hui; Zhang，Xumu
发表日期	2020-02-07
DOI	10.1021/acs.orglett.9b04624
发表期刊	ORGANIC LETTERS 影响因子和分区
ISSN	1523-7060
EISSN	1523-7052
卷号	22 期号:3页码:1108-1112
摘要	Rhodium-catalyzed asymmetric anti-Markovnikov hydroformylation of α-substituted acrylates/acrylamides has been developed. By employing the Rh/(S,S)-DTBM-YanPhos complex, a series of β-chiral linear aldehydes were obtained in high yields (up to 94% yield) and high enantioselectivities (up to 96% ee). The utility of this methodology is demonstrated by a gram-scale reaction and a concise synthetic route to chiral γ-butyrolactone.
相关链接	[Scopus记录]
收录类别	SCI ; IC ; CCR
语种	英语
重要成果	NI期刊
学校署名	通讯
资助项目	Shenzhen Nobel Prize Scientists Laboratory Project[C17783101]
WOS研究方向	Chemistry
WOS类目	Chemistry, Organic
WOS记录号	WOS:000513082700068
出版者	AMER CHEMICAL SOC
ESI学科分类	CHEMISTRY
Scopus记录号	2-s2.0-85078682088
来源库	Scopus
引用统计	被引频次[WOS]：14
成果类型	期刊论文
条目标识符	http://sustech.caswiz.com/handle/2SGJ60CL/73076
专题	理学院_化学系深圳格拉布斯研究院
作者单位	1.Key Laboratory of Biomedical Polymers of Ministry of Education,College of Chemistry and Molecular Sciences,Engineering Research Center of Organosilicon Compounds and Materials,Ministry of Education,Sauvage Center for Molecular Scieneces,Wuhan University,Wuhan, Hubei,430072,China 2.Shenzhen Grubbs Institute,Department of Chemistry,Southern University of Science and Technology,Shenzhen, Guangdong,518000,China
通讯作者单位	化学系; 深圳格拉布斯研究院
推荐引用方式 GB/T 7714	Li，Shuailong,Li，Zhuangxing,You，Cai,et al. Rhodium-Catalyzed Enantioselective Anti-Markovnikov Hydroformylation of α-Substituted Acryl Acid Derivatives[J]. ORGANIC LETTERS,2020,22(3):1108-1112.
APA	Li，Shuailong.,Li，Zhuangxing.,You，Cai.,Li，Xiuxiu.,Yang，Jiaxin.,...&Zhang，Xumu.(2020).Rhodium-Catalyzed Enantioselective Anti-Markovnikov Hydroformylation of α-Substituted Acryl Acid Derivatives.ORGANIC LETTERS,22(3),1108-1112.
MLA	Li，Shuailong,et al."Rhodium-Catalyzed Enantioselective Anti-Markovnikov Hydroformylation of α-Substituted Acryl Acid Derivatives".ORGANIC LETTERS 22.3(2020):1108-1112.