Mechanical stress induced astaxanthin production on a chip

Yao，Junyi1; Han，Sangil2; Kim，Hyun Soo3; Cho，Younghak4; Choi，Yoon E.2; Park，Jaewon1

2018

22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2018

3

1480-1481

Kaohsiung, Taiwan

Chemical and Biological Microsystems Society

Astaxanthin has been extensively studied in recent years due to its various pharmacological activities and high antioxidant capacity. Haematococcus pluvialis (H. pluvialis) is a type of microalgae that is capable of producing astaxanthin and it is also known to have the highest astaxanthin content in the nature. Here, we present a microfluidic culture platform that can culture flagellated stage of H. pluvialis under controlled mechanical stress for investigating its effect. The developed platform selectively cultured motile stage cells and approximately 15 times more astaxanthin accumulation was found with proper external mechanical stress applied during the 7 days of culture.

Astaxanthin Haematococcus pluvialis Mechanical stress Microalgae

第一 ; 通讯

英语

EI

National Natural Science Foundation of China[# 31750110453] ; Southern University of Science and Technology[# Y01231004]

20200908218349

Microorganisms

Biology:461.9

2-s2.0-85079791469

Scopus

1.Southern University of Science and Technology,China
2.Korea University,South Korea
3.Korea Institute of Machinery & Materials,South Korea
4.Seoul National University of Science and Technology,South Korea

Yao，Junyi,Han，Sangil,Kim，Hyun Soo,et al. Mechanical stress induced astaxanthin production on a chip[C]:Chemical and Biological Microsystems Society,2018:1480-1481.