The relationship between environmental exposure and asthma in adolescents aged 10–13 years: A cross-sectional study in Chongqing, China

Qiu，Chunlan1; Li，Wanxia1; Ping，Zhang1; Feng，Wei1; Zhao，Li1; Liu，Fangchao2; Liang，Fengchao3; Huang，Keyong2; An，Xizhou1; Xin，Chen1; Liang，Xiaohua1

2024-05-01

10.1016/j.cegh.2024.101615

Clinical Epidemiology and Global Health   影响因子和分区

2213-3984

Background: Asthma is one of the most prevalent diseases worldwide and is closely related to environmental exposure. The prevalence of asthma and the relationship between asthma and the duration of environmental exposure in adolescents has not been reported in Chongqing, China. Objectives: To examine the prevalence of asthma among adolescents in Chongqing and investigate the relationships between asthma and environmental exposure. Methods: The subjects were recruited from a previous cohort study. The data, demographics and respiratory characteristics were collected after a monthly follow-up visit. PM 2.5 concentrations were matched to the residential addresses of participants. Results: This study included 4146 samples (11.74 ± 0.71 years) and the prevalence of asthma was 3.98 % (165/4146). In terms of PM 2.5 exposure, the annual average PM 2.5 level was significantly higher in adolescents with asthma, and the annual average PM 2.5 was positively associated with asthma (OR = 1.252, 95%CI: 1.049, 1.495). After adjusting for multiple potential confounding factors, comparing with PM 2.5 concentration in the first interquartile range (Q1), seasonal PM 2.5 (OR = 1.791, 95%CI: 1.119, 2.866) and monthly PM 2.5 (OR = 1.484, 95%CI: 0.929, 2.373) in the third interquartile range (Q3), there was a statistically significant increased risk of asthma. In terms of weather-related factors, seasonal humidity (OR = 3.157, 95%CI: 1.168, 8.536), monthly humidity (OR = 2.397, 95%CI: 1.307, 4.397) and temperature (OR = 2.510, 95%CI: 1.157, 5.447), they were positively correlated with asthma. Conclusions: This study illustrated the impact of chronic exposure of PM 2.5, temperature and humidity on asthma in adolescents.

Adolescents Asthma Humidity PM 2.5 Temperature

ESCI

英语

其他

2-s2.0-85190742161

Scopus

1.Department of Epidemiology and Biostatistics,Children's Hospital of Chongqing Medical University,National Clinical Research Center for Child Health and Disorders,Ministry of Education Key Laboratory of Child Development and Disorders,Chongqing Key Laboratory of Pediatrics,Chongqing,China
2.Department of Epidemiology,Fuwai Hospital,National Center for Cardiovascular Diseases,Chinese Academy of Medical Sciences and Peking Union Medical College,Beijing,China
3.School of Public Health and Emergency Management,Southern University of Science and Technology,Shenzhen,China

Qiu，Chunlan,Li，Wanxia,Ping，Zhang,等. The relationship between environmental exposure and asthma in adolescents aged 10–13 years: A cross-sectional study in Chongqing, China[J]. Clinical Epidemiology and Global Health,2024,27.

Qiu，Chunlan.,Li，Wanxia.,Ping，Zhang.,Feng，Wei.,Zhao，Li.,...&Liang，Xiaohua.(2024).The relationship between environmental exposure and asthma in adolescents aged 10–13 years: A cross-sectional study in Chongqing, China.Clinical Epidemiology and Global Health,27.

Qiu，Chunlan,et al."The relationship between environmental exposure and asthma in adolescents aged 10–13 years: A cross-sectional study in Chongqing, China".Clinical Epidemiology and Global Health 27(2024).