| 题名 | Outdoor fine particulate matter exposure and telomere length in humans: A systematic review and meta-analysis |
| 作者 | |
| 通讯作者 | Yang，Xueli |
| 发表日期 | 2024-04-15
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| DOI | |
| 发表期刊 | |
| ISSN | 0147-6513
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| EISSN | 1090-2414
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| 卷号 | 275 |
| 摘要 | Although the association between changes in human telomere length (TL) and ambient fine particulate matter (PM) has been documented, there remains disagreement among the related literature. Our study conducted a systematic review and meta-analysis of epidemiological studies to investigate the health effects of outdoor PM exposure on human TL after a thorough database search. To quantify the overall effect estimates of TL changes associated with every 10 μg/m increase in PM exposure, we focused on two main topics, which were outdoor long-term exposure and prenatal exposure of PM. Additionally, we included a summary of short-term PM exposure and its impact on TL due to limited data availability. Our qualitative analysis included 20 studies with 483,600 participants. The meta-analysis showed a statistically significant association between outdoor PM exposure and shorter human TL, with pooled impact estimates (β) of −0.12 (95% CI: −0.20, −0.03, I= 95.4%) for general long-term exposure and −0.07 (95% CI: −0.15, 0.00, I= 74.3%) for prenatal exposure. In conclusion, our findings suggest that outdoor PM exposure may contribute to TL shortening, and noteworthy associations were observed in specific subgroups, suggesting the impact of various research variables. Larger, high-quality studies using standardized methodologies are necessary to strengthen these conclusions further. |
| 关键词 | |
| 相关链接 | [Scopus记录] |
| 收录类别 | |
| 语种 | 英语
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| 学校署名 | 第一
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| ESI学科分类 | ENVIRONMENT/ECOLOGY
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| Scopus记录号 | 2-s2.0-85188648538
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| 来源库 | Scopus
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| 引用统计 |
被引频次[WOS]：1
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| 成果类型 | 期刊论文 |
| 条目标识符 | http://sustech.caswiz.com/handle/2SGJ60CL/741207 |
| 专题 | 南方科技大学医学院_公共卫生及应急管理学院 |
| 作者单位 | 1.School of Public Health and Emergency Management,Southern University of Science and Technology,Shenzhen,518055,China 2.Department of Occupational and Environmental Health,School of Public Health,Tianjin Medical University,Tianjin,22 Qixiangtai Road, Heping District,300070,China |
| 第一作者单位 | 公共卫生及应急管理学院 |
| 第一作者的第一单位 | 公共卫生及应急管理学院 |
| 推荐引用方式 GB/T 7714 |
Wei，Bincai,Zhou，Yawen,Li，Qian,et al. Outdoor fine particulate matter exposure and telomere length in humans: A systematic review and meta-analysis[J]. Ecotoxicology and Environmental Safety,2024,275.
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| APA |
Wei，Bincai.,Zhou，Yawen.,Li，Qian.,Zhen，Shihan.,Wu，Qingyao.,...&Liang，Fengchao.(2024).Outdoor fine particulate matter exposure and telomere length in humans: A systematic review and meta-analysis.Ecotoxicology and Environmental Safety,275.
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| MLA |
Wei，Bincai,et al."Outdoor fine particulate matter exposure and telomere length in humans: A systematic review and meta-analysis".Ecotoxicology and Environmental Safety 275(2024).
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| 条目包含的文件 | 条目无相关文件。 | |||||
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