Clip-and-snare method with a pre-looping technique versus conventional method in the treatment of precancerous lesion and early gastric cancer: a retrospective study

Deng，Ruichong; Wu，Jiatong; Li，Defeng; Wu，Benhua; Shi，Ruiyue; Tian，Yanhui; Yao，Jun; Wang，Li Sheng

2024-12-01

10.1186/s12876-024-03231-w

BMC Gastroenterology   影响因子和分区

1471-230X

Background: Low grade intraepithelial neoplasia (LGIN) and high grade intraepithelial neoplasia (HGIN) are potential precancerous lesion of gastric neoplasms. Endoscopic submucosal dissection (ESD) is the first option for the treatment of precancerous lesion and early gastric cancer (EGC). Traction is an effective method to improve efficiency, and reduce complications during ESD. In this study, we shared a useful traction method using the clip-and-snare method with a pre-looping technique (CSM-PLT) for precancerous lesion and EGC. Methods: We retrospectively analyzed patients received ESD combined with CSM-PLT or conventional ESD from June 2018 to December 2021 in Shenzhen People’s hospital. The primary outcome was resection speed. Results: Forty-two patients were enrolled in ESD combined with CSM-PLT group and sixty-five patients in conventional ESD group respectively. Baseline characteristics were comparable among two groups (P>0.05). There were no significant differences in terms of R0 resection rate, en bloc resection rate (97.6% vs. 98.5%, P = 1.000 and 97.6% vs. 96.9%, P = 1.000, respectively), operation costs (933.7 (644.1-1102.4) dollars vs. 814.7 (614.6-988.3) dollars, P = 0.107), and hospital stays (8.0 ± 3.1 days vs. 7.3 ± 3.2 days, P = 0.236). In addition, no significant difference was observed with respect to complications (P>0.05). However, the resection speed of ESD combined with CSM-PLT was faster than that of conventional ESD (11.3 (9.4–14.9) mm/min vs. 8.0 (5.8–10.9) mm/min, P < 0.001), particularly lesions located in anterior wall and lesser curvature. In addition, the association between ESD combined with CSM-PLT and resection speed was still supported after propensity matching scores (PMS). Conclusions: CSM-PLT can help to improve ESD efficiency without reducing the en bloc resection rate or increasing the incidence of complications.

Clip-and-snare method with a pre-looping technique Early gastric cancer Endoscopic submucosal dissection Precancerous lesion

SCI

英语

第一

CLINICAL MEDICINE

2-s2.0-85193516820

Scopus

Department of Gastroenterology,The Second Clinical Medical College,The First Affiliated Hospital,Shenzhen People’s Hospital,Jinan University,Southern University of Science and Technology,Shenzhen,No.1017, Dongmen North Road, Luohu District,518020,China

Deng，Ruichong,Wu，Jiatong,Li，Defeng,et al. Clip-and-snare method with a pre-looping technique versus conventional method in the treatment of precancerous lesion and early gastric cancer: a retrospective study[J]. BMC Gastroenterology,2024,24(1).

Deng，Ruichong.,Wu，Jiatong.,Li，Defeng.,Wu，Benhua.,Shi，Ruiyue.,...&Wang，Li Sheng.(2024).Clip-and-snare method with a pre-looping technique versus conventional method in the treatment of precancerous lesion and early gastric cancer: a retrospective study.BMC Gastroenterology,24(1).

Deng，Ruichong,et al."Clip-and-snare method with a pre-looping technique versus conventional method in the treatment of precancerous lesion and early gastric cancer: a retrospective study".BMC Gastroenterology 24.1(2024).