A systematic review and bayesian meta-analysis of medical devices used in chronic pain management

Shetty，Ashish1,2,10; Delanerolle，Gayathri3,10; Deng，Chunli4; Thillainathan，Anish1; Cavalini，Heitor6; Yang，Xiaojie4,7; Bouchareb，Yassine11; Boyd，Amy9; Phiri，Peter5,6,10; Shi，Jian Qing4,6,8,10; Deer，Timothy12

2024-12-01

10.1038/s41598-024-63499-6

Scientific Reports   影响因子和分区

2045-2322

Whilst pharmacological therapies remain the cornerstone of pain management in chronic pain, factors including the current opioid epidemic have led to non-pharmacological techniques becoming a more attractive proposition. We explored the prevalence of medical device use and their treatment efficacy in non-cancer pain management. A systematic methodology was developed, peer reviewed and published in PROSPERO (CRD42021235384). Key words of medical device, pain management devices, chronic pain, lower back pain, back pain, leg pain and chronic pelvic pain using Science direct, PubMed, Web of Science, PROSPERO, MEDLINE, EMBASE, PorQuest and ClinicalTrials.gov. All clinical trials, epidemiology and mixed methods studies that reported the use of medical devices for non-cancer chronic pain management published between the 1st of January 1990 and the 30th of April 2022 were included. 13 studies were included in systematic review, of these 6 were used in the meta-analysis. Our meta-analysis for pain reduction showed that transcutaneous electrical nerve stimulation combined with instrument-assisted soft tissue mobilization treatment and pulsed electromagnetic therapy produced significant treatment on chronic lower back pain patients. Pooled evidence revealed the use of medical device related interventions resulted in 0.7 degree of pain reduction under a 0–10 scale. Significant improvement in disability scores, with a 7.44 degree reduction in disability level compared to a placebo using a 50 score range was also seen. Our analysis has shown that the optimal use of medical devices in a sustainable manner requires further research, needing larger cohort studies, greater gender parity, in a more diverse range of geographical locations.

SCI

英语

其他

2-s2.0-85195959237

Scopus

1.University College London Hospitals NHS Foundation Trust,London,United Kingdom
2.University College London,London,235, Euston Road,NW1 2BU,United Kingdom
3.Nuffield Department of Primary Care Health Sciences,University of Oxford,Oxford,OX3 7JX,United Kingdom
4.Southern University of Science and Technology,Shenzhen,518055,China
5.Psychology Department,Faculty of Environmental and Life Sciences,University of Southampton,Southampton,SO17 1BJ,United Kingdom
6.Southern Health NHS Foundation Trust,Southampton,SO40 2RZ,United Kingdom
7.School of Statistics and Mathematics,Yunnan University of Finance and Economics,Kunming,China
8.National Centre for Applied Mathematics Shenzhen,Shenzhen,China
9.Nuffield Department of Medicine,University of Oxford,Oxford,OX3 7JX,United Kingdom
10.Digital Evidence Based Medicine Lab,Oxford,United Kingdom
11.College of Medicine and Health Sciences,Sultan Qaboos University,Muscat,Oman
12.The Spine and Nerve Center of the Virginias,West Virginia University Hospitals,Charleston,United States

Shetty，Ashish,Delanerolle，Gayathri,Deng，Chunli,et al. A systematic review and bayesian meta-analysis of medical devices used in chronic pain management[J]. Scientific Reports,2024,14(1).

Shetty，Ashish.,Delanerolle，Gayathri.,Deng，Chunli.,Thillainathan，Anish.,Cavalini，Heitor.,...&Deer，Timothy.(2024).A systematic review and bayesian meta-analysis of medical devices used in chronic pain management.Scientific Reports,14(1).

Shetty，Ashish,et al."A systematic review and bayesian meta-analysis of medical devices used in chronic pain management".Scientific Reports 14.1(2024).