Exploring the biosynthetic possibilities of hydroxylated polybrominated diphenyl ethers from bromophenols in Prorocentrum donghaiense: Implications for bioremediation

Li，Bin1,2; Shi，Jianghong2; Xiang，Xueling2; Zhang，Mengtao2; Ge，Hui2; Sun，Shuhan2

2024-08-01

10.1016/j.chemosphere.2024.142611

Chemosphere   影响因子和分区

0045-6535

1879-1298

Bromophenols has been proven to synthesize hydroxylated polybrominated diphenyl ethers (OH-PBDEs), which may pose additional environmental and health risks in the process of bioremediation. In this study, the removal of 2,4-dibromophenol (2,4-DBP) and 2,4,6-tribromophenol (2,4,6-TBP) and the biosynthetic of OH-PBDEs by Prorocentrum donghaiense were explored. The removal efficiencies of 2,4-DBP and 2,4,6-TBP ranged from 32.71% to 76.89% and 31.15%–78.12%, respectively. Low concentrations of 2,4-DBP stimulated algal growth, while high concentrations were inhibitory. Furthermore, exposure to 10.00 mg L 2,4-DBP resulted in the detection of 2′-hydroxy-2,3′,4,5′-tetrabromodiphenyl ether (2′–OH–BDE-68) within P. donghaiense. In contrast, increasing concentrations of 2,4,6-TBP considerably inhibited P. donghaiense growth, with 4′-hydroxy-2,3′,4,5′,6-pentabromodiphenyl ether (4′–OH–BDE-121) detected within P. donghaiense under 5.00 mg L 2,4,6-TBP. Metabolomic analysis further revealed that the synthesized OH-PBDEs exhibited higher toxicity than their precursors and identified the oxidative coupling as a key biosynthetic mechanism. These findings confirm the capacity of P. donghaiense to remove bromophenols and biosynthesize OH-PBDEs from bromophenols, offering valuable insights into formulating algal bioremediation to mitigate bromophenol contamination.

Biosynthetic pathway Bromophenol Hydroxylated polybrominated diphenyl ethers Prorocentrum donghaiense Removal efficiencies

EI

英语

通讯

20242516264197

Biosynthesis ; Biotechnology ; Efficiency ; Ethers ; Health risks ; Hydroxylation ; Organic pollutants

Environmental Impact and Protection:454.2 ; Health Care:461.7 ; Biotechnology:461.8 ; Biochemistry:801.2 ; Chemical Reactions:802.2 ; Organic Compounds:804.1 ; Production Engineering:913.1

ENVIRONMENT/ECOLOGY

2-s2.0-85195868550

Scopus

1.School of Environment,Harbin Institute of Technology,Harbin,150090,China
2.Guangdong Provincial Key Laboratory of Soil and Groundwater Pollution Control,School of Environmental Science and Engineering,Southern University of Science and Technology,Shenzhen,518055,China

Li，Bin,Shi，Jianghong,Xiang，Xueling,et al. Exploring the biosynthetic possibilities of hydroxylated polybrominated diphenyl ethers from bromophenols in Prorocentrum donghaiense: Implications for bioremediation[J]. Chemosphere,2024,362.

Li，Bin,Shi，Jianghong,Xiang，Xueling,Zhang，Mengtao,Ge，Hui,&Sun，Shuhan.(2024).Exploring the biosynthetic possibilities of hydroxylated polybrominated diphenyl ethers from bromophenols in Prorocentrum donghaiense: Implications for bioremediation.Chemosphere,362.

Li，Bin,et al."Exploring the biosynthetic possibilities of hydroxylated polybrominated diphenyl ethers from bromophenols in Prorocentrum donghaiense: Implications for bioremediation".Chemosphere 362(2024).