Large-scale analysis of neural activity and connectivity from high-density electroencephalographic data

Taberna，Gaia Amaranta1; Samogin，Jessica1; Zhao，Mingqi1,2; Marino，Marco1,3; Guarnieri，Roberto1; Cuartas Morales，Ernesto1,4; Ganzetti，Marco1,5; Liu，Quanying1,6; Mantini，Dante1,7

2024-08-01

10.1016/j.compbiomed.2024.108704

Computers in Biology and Medicine   影响因子和分区

0010-4825

1879-0534

Introduction: High-density electroencephalography (hdEEG) is a technique used for the characterization of the neural activity and connectivity in the human brain. The analysis of EEG data involves several steps, including signal pre-processing, head modelling, source localization and activity/connectivity quantification. Visual check of the analysis steps is often necessary, making the process time- and resource-consuming and, therefore, not feasible for large datasets. Findings: Here we present the Noninvasive Electrophysiology Toolbox (NET), an open-source software for large-scale analysis of hdEEG data, running on the cross-platform MATLAB environment. NET combines all the tools required for a complete hdEEG analysis workflow, from raw signals to final measured values. By relying on reconstructed neural signals in the brain, NET can perform traditional analyses of time-locked neural responses, as well as more advanced functional connectivity and brain mapping analyses. The extracted quantitative neural data can be exported to provide broad compatibility with other software. Conclusions: NET is freely available (https://github.com/bind-group-kul/net) under the GNU public license for non-commercial use and open-source development, together with a graphical user interface (GUI) and a user tutorial. While NET can be used interactively with the GUI, it is primarily aimed at unsupervised automation to process large hdEEG datasets efficiently. Its implementation creates indeed a highly customizable program suitable for analysis automation and tight integration into existing workflows.

Brain activity Brain connectivity EEG Electrophysiological monitoring GUI Head modelling Signal processing Source localization

EI

英语

其他

20242316219394

Brain ; Brain mapping ; Electrophysiology ; Graphical user interfaces ; Large datasets ; MATLAB ; Neurons ; Open source software ; Open systems ; Statistics

Biomedical Engineering:461.1 ; Medicine and Pharmacology:461.6 ; Biology:461.9 ; Computer Peripheral Equipment:722.2 ; Computer Software, Data Handling and Applications:723 ; Data Processing and Image Processing:723.2 ; Computer Applications:723.5 ; Imaging Techniques:746 ; Mathematics:921 ; Mathematical Statistics:922.2

COMPUTER SCIENCE

2-s2.0-85195210152

Scopus

1.Movement Control and Neuroplasticity Research Group,KU Leuven,Leuven,3001,Belgium
2.Gansu Provincial Key Laboratory of Wearable Computing,School of Information Science and Engineering,Lanzhou University,Lanzhou,730000,China
3.Department of General Psychology,University of Padova,Padova,35131,Italy
4.Dirección Académica,Universidad Nacional de Colombia,La Paz,Sede de La Paz,202017,Colombia
5.Roche Pharma Research and Early Development (pRED),pRED Data & Analytics,Roche Innovation Center Basel,F. Hoffmann–La Roche Ltd,Basel,4070,Switzerland
6.Department of Biomedical Engineering,Southern University of Science and Technology,Shenzhen,518055,China
7.KU Leuven Brain Institute,KU Leuven,Leuven,3000,Belgium

Taberna，Gaia Amaranta,Samogin，Jessica,Zhao，Mingqi,et al. Large-scale analysis of neural activity and connectivity from high-density electroencephalographic data[J]. Computers in Biology and Medicine,2024,178.

Taberna，Gaia Amaranta.,Samogin，Jessica.,Zhao，Mingqi.,Marino，Marco.,Guarnieri，Roberto.,...&Mantini，Dante.(2024).Large-scale analysis of neural activity and connectivity from high-density electroencephalographic data.Computers in Biology and Medicine,178.

Taberna，Gaia Amaranta,et al."Large-scale analysis of neural activity and connectivity from high-density electroencephalographic data".Computers in Biology and Medicine 178(2024).