The first specific probe for pyrrolidine with multifunction by the interaction mechanism of atomic economic reaction

Cao，Xi Ying1; Huang，Yan2; Chen，Si Hong1; Yu，Shi Wei1; Chen，Zu Jia1; Li，Zhong Hao1; Zeng，Yu1; Chen，Nan2; Cao，Liang1,3; Wang，Zhao Yang1

2024-07-19

10.1016/j.isci.2024.110024

iScience   影响因子和分区

2589-0042

Pyrrolidine (PyD) has an important impact on the environment and human health. However, there is currently no method for trace detection of PyD. Here, we successfully designed diaminomethylene-4H-pyran (1) as the first specific fluorescent probe for PyD. Only by adding PyD to probe 1, there is blue fluorescence at 455 nm, and the color of the solution changes from colorless to yellow. The detection limit is 1.12 × 10 M, and the response time is less than 5 min. Meanwhile, probe 1 can also sense the gaseous PyD and detect PyD in actual water samples. Moreover, due to the low biological toxicity, probe 1 can detect the exogenous PyD in zebrafish. The preliminary mechanism shows that probe 1 and PyD undergo a combination-type chemical reaction to generate a new substance 1-PyD. Therefore, the 100% atom utilization reaction enables probe 1 to exhibit specific adsorption and removal of PyD.

Applied sciences Chemistry Natural sciences

SCI

英语

其他

2-s2.0-85195836078

Scopus

1.School of Chemistry,South China Normal University; Guangzhou Key Laboratory of Analytical Chemistry for Biomedicine; GDMPA Key Laboratory for Process Control and Quality Evaluation of Chiral Pharmaceuticals; Key Laboratory of Theoretical Chemistry of Environment,Ministry of Education,Guangzhou,510006,China
2.The Education Ministry Key Lab of Resource Chemistry,Joint International Research Laboratory of Resource Chemistry of Ministry of Education,Shanghai Key Laboratory of Rare Earth Functional Materials,College of Chemistry and Materials Science,Shanghai Normal University,Shanghai,200234,China
3.Shenzhen Key Laboratory of Cross-Coupling Reactions,Guangming Advanced Research Institute,Southern University of Science and Technology,Shenzhen,518055,China

Cao，Xi Ying,Huang，Yan,Chen，Si Hong,et al. The first specific probe for pyrrolidine with multifunction by the interaction mechanism of atomic economic reaction[J]. iScience,2024,27(7).

Cao，Xi Ying.,Huang，Yan.,Chen，Si Hong.,Yu，Shi Wei.,Chen，Zu Jia.,...&Wang，Zhao Yang.(2024).The first specific probe for pyrrolidine with multifunction by the interaction mechanism of atomic economic reaction.iScience,27(7).

Cao，Xi Ying,et al."The first specific probe for pyrrolidine with multifunction by the interaction mechanism of atomic economic reaction".iScience 27.7(2024).