南方科技大学知识苑(SUSTech KC): 基于气泡辅助技术的柔性蛋白凝胶触觉传感器制备研究

题名	基于气泡辅助技术的柔性蛋白凝胶触觉传感器制备研究
其他题名	A STUDY ON THE FABRICATION OF FLEXIBLE PROTEIN GEL TACTILE SENSORS VIA BUBBLE-ASSISTED TECHNIQUE
姓名	唐毓蔚
姓名拼音	TANG Yuwei
学号	12232167
学位类型	硕士
学位专业	085401 新一代电子信息技术
学科门类/专业学位类别	0854 电子信息
导师	王太宏
导师单位	电子与电气工程系
论文答辩日期	2024-05-07
论文提交日期	2024-07-01
学位授予单位	南方科技大学
学位授予地点	深圳
摘要	柔性传感技术作为柔性电子技术领域的关键研究方向之一，广泛应用于生理信号监测、医疗器械上，同时在物联网和可穿戴电子应用方面也有着具有巨大的潜力。然而，传统的柔性传感器一直存在生物不友好的问题，同时工艺流程复杂、价格昂贵。本研究致力于开发一种创新的生物兼容型柔性水凝胶传感器的制备技术，从制备效率及效益，器件性能，应用领域三个角度，阐述了传感器的优势。该技术的核心优势在于免除了传统意义上需手工进行的倒膜雕刻等复杂微结构制备步骤，促使微结构的自发形成，有效避免了有毒有害物质的产生，同时显著提升了反应速度与制备效率，从而提供了一种高效、经济的解决方案，以推动智能柔性传感器领域的发展。本课题以蛋清为基础材料，通过蛋清与氢氧化钠的碱性反应诱发凝胶化过程，并借助于铝箔与氢氧化钠间的化学反应自发产生的气泡，成功制备出含有气泡微结构的水凝胶传感器。其制备时间短，无需人工掩膜，五分钟即可自发完成介电层中微结构的制备，生产成本降至几分钱，极大的提高了生产效率，降低生产成本。根据杨氏弹性模量测试结果 571.4 kPa，本研究设计了范围为 0-470 kPa 的压力测试，将循环测试值设置为 10 kPa 与 470 kPa。在 0 至 470 kPa 的压力范围内传感器的灵敏度可到达 10.080 kPa−1。此外，对压力值分别设置为为 10 kPa 与 470 kPa，进行了 400 次循环测试，传感器依旧表现出了良好的电容响应，其响应时间更是小于 200 ms，充分证明了该传感器在高频动态压力变化下的可靠性和实用性。为了验证本研究制备的传感器应用范围，本课题设计了一个生理信号检测装置，可以从手机端收到实时的生理信号，实验进行了脉搏、握拳、按压、叠加等测试，并观察到了清晰、实时的运动信号，实现了实时、连续、准确、直观地监测日常生理信号的功能。最后本文还介绍了蛋清水凝胶制备的 4*4 的传感器阵列，该阵列可有效的知晓放置物体的位置和形状以及重力大小。以上结果表明，实验制备的传感器相较于其他生物材料的传感器，制备效率高、成本低，灵敏度较高，稳定性更好，为生物材料传感器技术提供了一条既简便又有效的微结构制备新途径。
其他摘要	As a key research direction in the field of flexible electronics, flexible sensing tech nology is widely used in physiological signal monitoring and medical devices, and it also possesses tremendous potential in the Internet of Things and wearable electronics applications. However, traditional flexible sensors have consistently presented issues with bio incompatibility, alongside complex manufacturing processes and high costs. This study is dedicated to developing an innovative preparation technology for biocompatible flexible hydrogel sensors, discussing the advantages of the sensors from three perspectives: preparation efficiency and effectiveness, device performance, and application areas. The core advantage of this technology is that it eliminates the need for manual and complex microstructure preparation steps such as membrane casting traditionally required, facilitating the spontaneous formation of microstructures, effectively preventing the production of toxic substances, and significantly enhancing reaction speed and preparation efficiency. This provides an efficient and economical solution to advance the development of the smart flexible sensor field. This project uses egg white as the base material, where the alkaline reaction between egg white and sodium hydroxide induces gelation, and the chemical reaction between aluminum foil and sodium hydroxide spontaneously generates bubbles, successfully producing a hydrogel sensor with bubble microstructures. The preparation process is short, requires no manual masking, and can spontaneously complete the microstructure formation in the dielectric layer in five minutes, reducing production costs to mere cents and significantly improving production efficiency and cost-effectiveness. Based on Young’s modulus test results of 571.4 kPa, this study designed a pressure test range from 0 to 470 kPa, with cyclic test values set at 10 kPa and 470 kPa. Within the 0 to 470 kPa pressure range, the sensor’s sensitivity can reach up to 10.080 kPa−1. Furthermore, 400 cyclic tests were conducted at pressures set at 10 kPa and 470 kPa, where the sensor still demonstrated good capacitive response, and its response time was even less than 200 ms, fully proving the sensor’s reliability and practicality under high-frequency dynamic pressure changes. To verify the application range of the sensors prepared in this study, a physiological signal detection device was designed that can receive real time physiological signals from a mobile device. Tests including pulse measurement, fist clenching, compression, and overlay were conducted, observing clear, real-time motion signals, achieving real-time, continuous, accurate, and intuitive monitoring of daily physiological signals. Lastly, the paper introduces a 4x4 sensor array prepared from egg white hydrogel, which effectively identifies the placement, shape, and weight of objects. These results indicate that the sensors prepared in the experiment, compared to other biometric sensors, have higher preparation efficiency, lower cost, higher sensitivity, and better stability, providing a simple and effective new pathway for the preparation of microstructures in biomaterial sensor technology.
关键词	蛋白凝胶微结构气泡无掩膜工艺柔性触觉传感器
其他关键词	Protein Hydrogel; Microstructure; Bubbles; Maskless Process; Flexible Tactile Sensor
语种	中文
培养类别	独立培养
入学年份	2022
学位授予年份	2024-06
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所在学位评定分委会	电子科学与技术
国内图书分类号	TP212
来源库	人工提交
成果类型	学位论文
条目标识符	http://sustech.caswiz.com/handle/2SGJ60CL/778796
专题	工学院_电子与电气工程系
推荐引用方式 GB/T 7714	唐毓蔚. 基于气泡辅助技术的柔性蛋白凝胶触觉传感器制备研究[D]. 深圳. 南方科技大学,2024.

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