南方科技大学知识苑(SUSTech KC): Synthesis of novel silver-loaded clay AgF@Hec for the prevention of dental caries <i>in vitro</i>

题名	Synthesis of novel silver-loaded clay AgF@Hec for the prevention of dental caries in vitro
作者	Wang, Y. S.1 ; Shi, Y. X.1 ; Liu, Q. Q.1 ; Hu, L. Q.1 ; Ma, F. B.1 ; Zhang, J. R.1 ; Tang, K. M.1,2; Tang, B.1,4 ; Dai, J.3
通讯作者	Tang, B.; Dai, J.
发表日期	2024-07-01
DOI	10.1088/1748-605X/ad51c1
发表期刊	BIOMEDICAL MATERIALS 影响因子和分区
ISSN	1748-6041
EISSN	1748-605X
卷号	19 期号:4
摘要	Dental caries, a chronic infectious disease characterized by tooth mineral loss caused by plaque, is one of the major global public health problems. Silver diamine fluoride (SDF) has been proven to be a highly effective anti-caries drug due to its high bacterial inhibition and remineralization ability. However, the SDF solution is unstable, which immensely limits its clinical application. Therefore, new silver-load clay named AgF@Hec was designed by replacing the NH3 with hectorite in this study. Fourier transform infrared spectroscopy and x-ray diffraction spectroscopy were employed to confirm the structure of AgF@Hec. Dynamic light scattering analysis was used to reveal the effect of different hectorite concentrations on the stability of AgF@Hec. Moreover, AgF@Hec exhibits significant remineralization and hardness recovery of the initial carious lesions. Bacteriostatic experiments also proved that it has a significant inhibitory effect on A. Viscosus, S. mutans, S. sanguinis, S. salivarius, Lactobacillus sp. and both gram-positive and gram-negative bacteria. We therefore believed that AgF@Hec should be a promising biomaterial that can be applied in the prevention of dental caries.
关键词	dental caries sliver hectorite biomaterial
相关链接	[来源记录]
收录类别	SCI ; EI
语种	英语
学校署名	第一 ; 通讯
资助项目	the National Foundation of Science and Technology[20220808170713001] ; Science Technology and Innovation Committee of Clinical Oral Investigations Shenzhen Municipality, China[2019YFA0906004] ; National Key Research and Development Program of China[11872200] ; National Foundation of Science and Technology[2022B1212010003] ; Guangdong Provincial Key Laboratory of Advanced Biomaterials["KCXFZ20211020174805009","JSGG20200225151916021"]
WOS研究方向	Engineering ; Materials Science
WOS类目	Engineering, Biomedical ; Materials Science, Biomaterials
WOS记录号	WOS:001251660500001
出版者	IOP Publishing Ltd
EI入藏号	20242616440364
EI主题词	Amines ; Ammonia ; Bacteria ; Fluorine compounds ; Light scattering
EI分类号	Light/Optics:741.1 ; Chemistry:801 ; Organic Compounds:804.1 ; Inorganic Compounds:804.2
来源库	Web of Science
引用统计
成果类型	期刊论文
条目标识符	http://sustech.caswiz.com/handle/2SGJ60CL/787646
专题	工学院_生物医学工程系
作者单位	1.Southern Univ Sci & Technol, Dept Biomed Engn, Shenzhen, Peoples R China 2.ShenZhen Coll Int Educ, Shenzhen, Peoples R China 3.Shenzhen Univ, Gen Hosp, Inst Stomatol, Dept Stomatol, Shenzhen, Peoples R China 4.Guangdong Prov Key Lab Adv Biomat, Shenzhen, Peoples R China
第一作者单位	生物医学工程系
通讯作者单位	生物医学工程系
第一作者的第一单位	生物医学工程系
推荐引用方式 GB/T 7714	Wang, Y. S.,Shi, Y. X.,Liu, Q. Q.,et al. Synthesis of novel silver-loaded clay AgF@Hec for the prevention of dental caries in vitro[J]. BIOMEDICAL MATERIALS,2024,19(4).
APA	Wang, Y. S..,Shi, Y. X..,Liu, Q. Q..,Hu, L. Q..,Ma, F. B..,...&Dai, J..(2024).Synthesis of novel silver-loaded clay AgF@Hec for the prevention of dental caries in vitro.BIOMEDICAL MATERIALS,19(4).
MLA	Wang, Y. S.,et al."Synthesis of novel silver-loaded clay AgF@Hec for the prevention of dental caries in vitro".BIOMEDICAL MATERIALS 19.4(2024).