Water and Air Stable Copper(I) Complexes of Tetracationic Catenane Ligands for Oxidative C-C Cross-Coupling

Tang, Man Pang1; Zhu, Lihui1,2; Deng, Yulin1; Shi, Yi-Xiang1; Lai, Samuel Kin-Man1; Mo, Xiaoyong1; Pang, Xin-Yu4; Liu, Chunyu5; Jiang, Wei4; Tse, Edmund Chun Ming1,3; Au-Yeung, Ho Yu1,2,3

2024-06-01

10.1002/anie.202405971

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION   影响因子和分区

1433-7851

1521-3773

["Aqueous soluble and stable Cu(I) molecular catalysts featuring a catenane ligand composed of two dicationic, mutually repelling but mechanically interlocked macrocycles are reported. The ligand interlocking not only fine-tunes the coordination sphere and kinetically stabilizes the Cu(I) against air oxidation and disproportionation, but also buries the hydrophobic portions of the ligands and prevents their dissociation which are necessary for their good water solubility and a sustained activity. These catenane Cu(I) complexes can catalyze the oxidative C-C coupling of indoles and tetrahydroisoquinolines in water, using H2O2 as a green oxidant with a good substrate scope. The successful use of catenane ligands in exploiting aqueous Cu(I) catalysis thus highlights the many unexplored potential of mechanical bond as a design element for exploring transition metal catalysis under challenging conditions.","Copper(I) molecular catalysts that are water soluble and stable against oxidative degradation are obtained by the strategic use of multiply charged catenane ligands. By using the new catalysts, oxidative C-C cross-coupling is realized in water using H2O2 as a green and convenient oxidant, highlighting the potential of ligand interlocking in leveraging transition metal catalysis under challenging conditions. image"]

catenane cationic ligands copper mechanical interlocking oxidative coupling

SCI ; EI

英语

其他

University Grants Committee["17313222","C7075-21G"]

Chemistry

Chemistry, Multidisciplinary

WOS:001237376300001

WILEY-V C H VERLAG GMBH

20242316204185

Catalysis ; Copper compounds ; Transition metals

Metallurgy and Metallography:531 ; Physical Chemistry:801.4 ; Chemical Reactions:802.2

CHEMISTRY

Web of Science

1.Univ Hong Kong, Dept Chem, Pokfulam Rd, Hong Kong, Peoples R China
2.Univ Hong Kong, State Key Lab Synthet Chem, Pokfulam Rd, Hong Kong, Peoples R China
3.Univ Hong Kong, CAS HKU Joint Lab New Mat, Pokfulam Rd, Hong Kong, Peoples R China
4.South Univ Sci & Technol China, Dept Chem, Xueyuan Blvd 1088, Shenzhen 518055, Peoples R China
5.Jiangnan Univ, Minist Educ, Key Lab Ecotext, Wuxi 100083, Peoples R China

Tang, Man Pang,Zhu, Lihui,Deng, Yulin,et al. Water and Air Stable Copper(I) Complexes of Tetracationic Catenane Ligands for Oxidative C-C Cross-Coupling[J]. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION,2024,63.

Tang, Man Pang.,Zhu, Lihui.,Deng, Yulin.,Shi, Yi-Xiang.,Lai, Samuel Kin-Man.,...&Au-Yeung, Ho Yu.(2024).Water and Air Stable Copper(I) Complexes of Tetracationic Catenane Ligands for Oxidative C-C Cross-Coupling.ANGEWANDTE CHEMIE-INTERNATIONAL EDITION,63.

Tang, Man Pang,et al."Water and Air Stable Copper(I) Complexes of Tetracationic Catenane Ligands for Oxidative C-C Cross-Coupling".ANGEWANDTE CHEMIE-INTERNATIONAL EDITION 63(2024).