Enantioselective Si-H Insertion of Arylvinyldiazoesters Promoted by Rhodium(I)/Diene Complexes

Li, Ziyan1,2; Liu, Jian-Guo1,2; Zhang, Wen-Ping1,2; Xu, Ming-Hua1,2,3

2024-06-10

10.1002/adsc.202400241

ADVANCED SYNTHESIS & CATALYSIS   影响因子和分区

1615-4150

1615-4169

["An enantioselective Si-H insertion between alpha-arylvinyldiazoesters and silanes has been developed by employing rhodium(I)/chiral diene complex as the catalyst. This protocol offers a catalytic asymmetric approach to various chiral silanes containing alpha-arylvinyl functionality at room temperature with good enantiocontrol (89-99% ee). Transformation of the resulting enantiomerically enriched alpha-arylvinyl-alpha-silyl esters led to a variety of other valuable building blocks. The deuterium kinetic isotope effect experiments revealed a rhodium(I)-mediated concerted Si-H insertion mechanism.","image"]

asymmetric catalysis metal carbene Si-H insertion diene ligands allylsilanes

SCI

英语

第一 ; 通讯

Shenzhen Science and Technology Innovation Commission[JCYJ20200109141408054] ; Guangdong Science and Technology Department[2019CX01Y251] ; Guangdong Provincial Key Laboratory of Catalysis["2020B121201002","(1R,4R)-5-phenylbicyclo"] ; null[21971103]

Chemistry

Chemistry, Applied ; Chemistry, Organic

WOS:001222773000001

WILEY-V C H VERLAG GMBH

Web of Science

1.Southern Univ Sci & Technol, Shenzhen Grubbs Inst, Shenzhen 518055, Peoples R China
2.Southern Univ Sci & Technol, Dept Chem, Guangdong Prov Key Lab Catalysis, Shenzhen 518055, Peoples R China
3.Henan Normal Univ, Sch Chem & Chem Engn, Xinxiang 453007, Henan, Peoples R China

Li, Ziyan,Liu, Jian-Guo,Zhang, Wen-Ping,et al. Enantioselective Si-H Insertion of Arylvinyldiazoesters Promoted by Rhodium(I)/Diene Complexes[J]. ADVANCED SYNTHESIS & CATALYSIS,2024,366(11).

Li, Ziyan,Liu, Jian-Guo,Zhang, Wen-Ping,&Xu, Ming-Hua.(2024).Enantioselective Si-H Insertion of Arylvinyldiazoesters Promoted by Rhodium(I)/Diene Complexes.ADVANCED SYNTHESIS & CATALYSIS,366(11).

Li, Ziyan,et al."Enantioselective Si-H Insertion of Arylvinyldiazoesters Promoted by Rhodium(I)/Diene Complexes".ADVANCED SYNTHESIS & CATALYSIS 366.11(2024).