H6N2 reassortant avian influenza virus isolate in wild birds in Jiangxi Province, China

Wang, Yingjie1; Li, Xiang1; Lv, Xinru1; Li, Yi1; An, Qing1; Xiu, Yang1; Lv, Xiangtong1; Song, Haozhuo1; Zhou, Changyu1,3; Xu, Qiushi1,4,5; Qiao, Dan1; Yang, Siyuan2; Chai, Hongliang1; Zeng, Xiangwei1

2024-06-01

10.1007/s11262-024-02068-5

VIRUS GENES   影响因子和分区

0920-8569

1572-994X

H6 avian influenza virus is widely prevalent in wild birds and poultry and has caused human infection in 2013 in Taiwan, China. During our active influenza surveillance program in wild waterfowl at Poyang Lake, Jiangxi Province, an H6N2 AIV was isolated and named A/bean goose/JiangXi/452-4/2013(H6N2). The isolate was characterized as a typical low pathogenic avian influenza virus (LPAIV) due to the presence of the amino acid sequence PQIETR down arrow GLFGAI at the cleavage site of the hemagglutinin (HA) protein. The genetic evolution analysis revealed that the NA gene of the isolate originated from North America and exhibited the highest nucleotide identity (99.29%) with a virus recovered from wild bird samples in North America, specifically A/bufflehead/California/4935/2012(H11N2). Additionally, while the HA and PB1 genes belonged to the Eurasian lineage, they displayed frequent genetic interactions with the North American lineage. The remaining genes showed close genetic relationships with Eurasian viruses. The H6N2 isolate possessed a complex genome, indicating it is a multi-gene recombinant virus with genetic material from both Eurasian and North American lineages.

Avian influenza virus Wild bird Recombination North American lineages

SCI

英语

其他

Heilongjiang Natural Science Foundation Program[LH2023C046] ; National Natural Science Foundation of China[31970501] ; Fundamental Research Funds for the Central Universities[2572022CG01] ; null[202310225111]

Genetics & Heredity ; Virology

Genetics & Heredity ; Virology

WOS:001220430600001

SPRINGER

MOLECULAR BIOLOGY & GENETICS

Web of Science

1.Northeast Forestry Univ, Coll Wildlife & Protected Area, Harbin 150040, Peoples R China
2.Heilongjiang Vocat Coll Nationalities, Harbin 150066, Peoples R China
3.Sichuan Univ, Coll Life Sci, Anim Dis Prevent & Food Safety Key Lab Sichuan Pro, Chengdu 610064, Peoples R China
4.Harbin Inst Technol, Harbin 150001, Peoples R China
5.Southern Univ Sci & Technol, Sch Life Sci, Dept Syst Biol, Shenzhen Key Lab Gene Regulat & Syst Biol, Shenzhen 518055, Peoples R China

Wang, Yingjie,Li, Xiang,Lv, Xinru,et al. H6N2 reassortant avian influenza virus isolate in wild birds in Jiangxi Province, China[J]. VIRUS GENES,2024,60(3).

Wang, Yingjie.,Li, Xiang.,Lv, Xinru.,Li, Yi.,An, Qing.,...&Zeng, Xiangwei.(2024).H6N2 reassortant avian influenza virus isolate in wild birds in Jiangxi Province, China.VIRUS GENES,60(3).

Wang, Yingjie,et al."H6N2 reassortant avian influenza virus isolate in wild birds in Jiangxi Province, China".VIRUS GENES 60.3(2024).