Significance of High-Frequency Sonography for the Subclinical Progression of Rheumatoid Arthritis

Li, Yudan1; Zhang, Ziteng2; Liu, Cuicui3; Kang, Zhilong2; Li, Zhiyan1

2024-05-01

10.1002/jum.16474

JOURNAL OF ULTRASOUND IN MEDICINE   影响因子和分区

0278-4297

1550-9613

ObjectivesThis study aims to investigate the use of high-frequency sonography as a tool for detecting inflammatory and destructive changes in the hand and foot joints of patients with early and long-term RA. MethodsThis study employs a prospective cohort design involving 162 patients diagnosed with Rheumatoid arthritis (RA) who meet the American College of Rheumatology/European League Against Rheumatism (ACR/EULAR) classification criteria. Patients were divided into two groups based on disease duration: Group 1 (n = 74) included patients with a disease duration of up to 2 years, or early & Rcy;& Acy; (ERA;), Group 2 (n = 88) consisted of patients with a disease duration exceeding 2 years, or long-term persistent & Rcy;& Acy; (LtRA). All patients underwent a clinical assessment of their joints, as well as radiography and arthrosonography, at the beginning of the study and again at 6 and 12 months later. ResultsIn the general group of patients, ultrasound examination revealed signs of synovitis in the joints of the hands more frequently (66%) compared with clinical examination (56% by a number of swollen joints [NSJ] and 55% by a number of painful joints [NPJ], P < .01). After 6 months of treatment, 12% of the patients achieved full US remission and 24% achieved partial US remission. ConclusionsWithin the scope of comprehensive RA diagnostics, arthrosonography of the joints of the hands and feet, utilizing a combination of greyscale and power Doppler, may surpass radiography in detecting early RA. This method allows for a more accurate assessment of disease activity and progression rates.

diagnostics rheumatoid arthritis sonography synovitis ultrasound monitoring of therapeutic response

SCI ; EI

英语

第一 ; 通讯

Acoustics ; Radiology, Nuclear Medicine & Medical Imaging

Acoustics ; Radiology, Nuclear Medicine & Medical Imaging

WOS:001215930500001

WILEY

20241916063787

Diagnosis ; Diseases ; Patient monitoring ; Patient treatment ; Radiography

Medicine and Pharmacology:461.6 ; Imaging Techniques:746 ; Ultrasonic Applications:753.3

CLINICAL MEDICINE

Web of Science

1.Southern Univ Sci & Technol, Shenzhen Third Peoples Hosp, Affiliated Hosp 2, Ultrasonog Div, Shenzhen, Peoples R China
2.Southern Univ Sci & Technol, Shenzhen Third Peoples Hosp, Affiliated Hosp 2, Hepatobiliary Surg Div, Shenzhen, Peoples R China
3.Sun Yat Sen Univ, Sun Yat Sen Mem Hosp, Dept Rehabil Med, Guangzhou, Peoples R China

Li, Yudan,Zhang, Ziteng,Liu, Cuicui,et al. Significance of High-Frequency Sonography for the Subclinical Progression of Rheumatoid Arthritis[J]. JOURNAL OF ULTRASOUND IN MEDICINE,2024,43:1509-1520.

Li, Yudan,Zhang, Ziteng,Liu, Cuicui,Kang, Zhilong,&Li, Zhiyan.(2024).Significance of High-Frequency Sonography for the Subclinical Progression of Rheumatoid Arthritis.JOURNAL OF ULTRASOUND IN MEDICINE,43,1509-1520.

Li, Yudan,et al."Significance of High-Frequency Sonography for the Subclinical Progression of Rheumatoid Arthritis".JOURNAL OF ULTRASOUND IN MEDICINE 43(2024):1509-1520.