南方科技大学知识苑(SUSTech KC): Vitamin D Status of Preterm Newborns at Approximately 4 Weeks of Age in Shenzhen, China: A Retrospective Observational Cohort Study Conducted Across Two Centers

题名	Vitamin D Status of Preterm Newborns at Approximately 4 Weeks of Age in Shenzhen, China: A Retrospective Observational Cohort Study Conducted Across Two Centers
作者	Guo, Yanping 1; Yu, Zhangbin 2; Tu, Huiying 2; Zheng, Biying 1; Li, Jiamin 1; Liu, Ying 1
通讯作者	Guo, Yanping; Liu, Ying
发表日期	2024
DOI	10.2147/RRN.S450403
发表期刊	RESEARCH AND REPORTS IN NEONATOLOGY 影响因子和分区
EISSN	1179-9935
卷号	14
摘要	Background and Objectives: To examine the correlation between the concentration of vitamin D (VD) in venous blood at approximately 4 weeks of age (+/- 4 weeks of age) and neonatal outcomes in preterm infants (birth weight < 1500 g or gestational age < 32 weeks) in two neonatal intensive care units (NICUs) located in Shenzhen, China. Methods and Study Design: Preterm infants were split into two groups based on their VD concentration at +/- 4 weeks of age: VD insufficiency (VDI) group (<= 20 ng/mL) and VD sufficient (VDS) group (> 20 ng/mL). Binary logistic regression analysis was used to examine relationships between outcomes and VDI. Results: Of 230 infants in total, 119 (51.7%) were assigned to the VDI group and 111 to the VDS group (48.3%). No correlation was found between serum VD at +/- 4 weeks of age and gestational age (p> 0.05). The starting point of the two groups for oral VD intake did not differ significantly (p> 0.05). At +/- 4 weeks of age, oral VD dose (P< 0.05) was greater in the VDS group. Gestational diabetes mellitus was associated with VDI (OR=1.94, 95% CI 1.01- 3.75, p=0.047) after controlling for this risk. Following correction for gestational age and oral VD dosage at +/- 4 weeks old, VDI was also linked to a significant risk of retinopathy of prematurity (OR=2.00, 95% CI 1.08- 3.68, p< 0.027). Conclusion: Preterm newborns (gestational age < 32 weeks or birth age < 1500 g) in NICUs in Shenzhen, China continue to have significantly high VDI. Higher VDI is associated with gestational diabetes mellitus and retinopathy of prematurity.
关键词	very preterm birth very low birth weight infant vitamin D 4 weeks of age outcome
相关链接	[来源记录]
收录类别	ESCI
语种	英语
学校署名	其他
资助项目	General Program for Clinical Research at Peking University Shenzhen Hospital[LCYJ2020013]
WOS研究方向	Pediatrics
WOS类目	Pediatrics
WOS记录号	WOS:001181847400001
出版者	DOVE MEDICAL PRESS LTD
来源库	Web of Science
引用统计
成果类型	期刊论文
条目标识符	http://sustech.caswiz.com/handle/2SGJ60CL/788907
专题	南方科技大学第一附属医院
作者单位	1.Peking Univ, Shenzhen Hosp, Dept Pediat, Shenzhen, Guangdong, Peoples R China 2.Southern Univ Sci & Technol, Jinan Univ, Affiliated Hosp 1, Dept Neonatol,Shenzhen Peoples Hosp,Clin Med Coll, Shenzhen, Guangdong, Peoples R China
推荐引用方式 GB/T 7714	Guo, Yanping,Yu, Zhangbin,Tu, Huiying,et al. Vitamin D Status of Preterm Newborns at Approximately 4 Weeks of Age in Shenzhen, China: A Retrospective Observational Cohort Study Conducted Across Two Centers[J]. RESEARCH AND REPORTS IN NEONATOLOGY,2024,14.
APA	Guo, Yanping,Yu, Zhangbin,Tu, Huiying,Zheng, Biying,Li, Jiamin,&Liu, Ying.(2024).Vitamin D Status of Preterm Newborns at Approximately 4 Weeks of Age in Shenzhen, China: A Retrospective Observational Cohort Study Conducted Across Two Centers.RESEARCH AND REPORTS IN NEONATOLOGY,14.
MLA	Guo, Yanping,et al."Vitamin D Status of Preterm Newborns at Approximately 4 Weeks of Age in Shenzhen, China: A Retrospective Observational Cohort Study Conducted Across Two Centers".RESEARCH AND REPORTS IN NEONATOLOGY 14(2024).