| 题名 | Hydrogel Loaded with Components for Therapeutic Applications in Hypertrophic Scars and Keloids |
| 作者 | |
| 通讯作者 | Zhong, Yixiu; Zhang, Jianglin |
| 发表日期 | 2024
|
| DOI | |
| 发表期刊 | |
| ISSN | 1178-2013
|
| 卷号 | 19 |
| 摘要 | Hypertrophic scars and keloids are common fibroproliferative diseases following injury. Patients with pathologic scars suffer from impaired quality of life and psychological health due to appearance disfiguration, itch, pain, and movement disorders. Recently, the advancement of hydrogels in biomedical fields has brought a variety of novel materials, methods and therapeutic targets for treating hypertrophic scars and keloids, which exhibit broad prospects. This review has summarized current research on hydrogels and loaded components used in preventing and treating hypertrophic scars and keloids. These hydrogels attenuate keloid and hypertrophic scar formation and progression by loading organic chemicals, drugs, or bioactive molecules (such as growth factors, genes, proteins/peptides, and stem cells/exosomes). Among them, smart hydrogels (a very promising method for loading many types of bioactive components) are currently favoured by researchers. In addition, combining hydrogels and current therapy (such as laser or radiation therapy, etc.) could improve the treatment of hypertrophic scars and keloids. Then, the difficulties and limitations of the current research and possible suggestions for improvement are listed. Moreover, we also propose novel strategies for facilitating the construction of target multifunctional hydrogels in the future. |
| 关键词 | |
| 相关链接 | [来源记录] |
| 收录类别 | |
| 语种 | 英语
|
| 学校署名 | 通讯
|
| 资助项目 | National Natural Science Foundation of China["82073019","82073018","82202851"]
; Shenzhen Science and Technology Innovation Commission, China (Natural Science Foundation of Shenzhen)["JCYJ20210324113001005","JCYJ20210324114212035","JCYJ20220530151817038"]
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| WOS研究方向 | Science & Technology - Other Topics
; Pharmacology & Pharmacy
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| WOS类目 | Nanoscience & Nanotechnology
; Pharmacology & Pharmacy
|
| WOS记录号 | WOS:001153010100001
|
| 出版者 | |
| 来源库 | Web of Science
|
| 引用统计 |
被引频次[WOS]：1
|
| 成果类型 | 期刊论文 |
| 条目标识符 | http://sustech.caswiz.com/handle/2SGJ60CL/789338 |
| 专题 | 南方科技大学第一附属医院 |
| 作者单位 | 1.Jinan Univ, Shenzhen Peoples Hosp, Clin Med Coll 2, Dept Dermatol, Guangzhou, Peoples R China 2.Southern Univ Sci & Technol, Affiliated Hosp 1, Shenzhen, Guangdong, Peoples R China 3.Southern Med Univ, Nanfang Hosp, Dept Dermatol, Guangzhou, Peoples R China |
| 第一作者单位 | 南方科技大学第一附属医院 |
| 通讯作者单位 | 南方科技大学第一附属医院 |
| 推荐引用方式 GB/T 7714 |
Zhong, Yixiu,Zhang, Youfan,Lu, Beibei,et al. Hydrogel Loaded with Components for Therapeutic Applications in Hypertrophic Scars and Keloids[J]. INTERNATIONAL JOURNAL OF NANOMEDICINE,2024,19.
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| APA |
Zhong, Yixiu.,Zhang, Youfan.,Lu, Beibei.,Deng, Zhenjun.,Zhang, Zhiwen.,...&Zhang, Jianglin.(2024).Hydrogel Loaded with Components for Therapeutic Applications in Hypertrophic Scars and Keloids.INTERNATIONAL JOURNAL OF NANOMEDICINE,19.
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| MLA |
Zhong, Yixiu,et al."Hydrogel Loaded with Components for Therapeutic Applications in Hypertrophic Scars and Keloids".INTERNATIONAL JOURNAL OF NANOMEDICINE 19(2024).
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| 条目包含的文件 | 条目无相关文件。 | |||||
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