南方科技大学知识苑(SUSTech KC): A review of protocols for engineering human cardiac organoids

题名	A review of protocols for engineering human cardiac organoids
作者	Wu, Fujian 1,2,3; He, Qian 4; Li, Furong 3; Yang, Xiaofei 1,3
通讯作者	Yang, Xiaofei
发表日期	2023-09-01
DOI	10.1016/j.heliyon.2023.e19938
发表期刊	HELIYON 影响因子和分区
EISSN	2405-8440
卷号	9 期号:9
摘要	The use of human cardiac organoids (hCOs) as 3D in vitro models for cardiovascular research has shown great promise. Human pluripotent stem cells (hPSCs) have proven to be a potent source for engineering hCOs. However, various protocols for generating hCOs from hPSCs result in significant differences in heart development, maturity, complexity, vascularization, and spatial structure, all of which can influence their functional and physiological properties. This protocol review aims to highlight different strategies for generating hCOs using hPSCs while also critically discussing their challenges and limitations.
关键词	Review Protocols hPSC Cardiac organoids Differentiation
相关链接	[来源记录]
收录类别	SCI
语种	英语
学校署名	第一 ; 通讯
资助项目	National Natural Science Foundation of China["81800685","81670702"] ; Natural Science Foundation of Guangdong[2018A030310039] ; Science and Technology Project of Shenzhen[GJHZ20180413181702008]
WOS研究方向	Science & Technology - Other Topics
WOS类目	Multidisciplinary Sciences
WOS记录号	WOS:001140574900001
出版者	CELL PRESS
来源库	Web of Science
引用统计
成果类型	期刊论文
条目标识符	http://sustech.caswiz.com/handle/2SGJ60CL/789362
专题	南方科技大学第一附属医院
作者单位	1.Jinan Univ, Southern Univ Sci & Technol, Shenzhen Peoples Hosp, Affiliated Hosp 1,Clin Med Coll 2,Translat Med Col, Shenzhen 518055, Guangdong, Peoples R China 2.Jinan Univ, Postdoctoral Sci Res Stn Basic Med, Guangzhou 510632, Peoples R China 3.Guangdong Engn Technol Res Ctr Stem Cell & Cell Th, Shenzhen Immune Cell Therapy Publ Serv Platform, Shenzhen Key Lab Stem Cell Res & Clin Transformat, Shenzhen 518020, Peoples R China 4.Shenzhen Polytech, Sch Food & Drug, Shenzhen 518055, Peoples R China
第一作者单位	南方科技大学第一附属医院
通讯作者单位	南方科技大学第一附属医院
第一作者的第一单位	南方科技大学第一附属医院
推荐引用方式 GB/T 7714	Wu, Fujian,He, Qian,Li, Furong,et al. A review of protocols for engineering human cardiac organoids[J]. HELIYON,2023,9(9).
APA	Wu, Fujian,He, Qian,Li, Furong,&Yang, Xiaofei.(2023).A review of protocols for engineering human cardiac organoids.HELIYON,9(9).
MLA	Wu, Fujian,et al."A review of protocols for engineering human cardiac organoids".HELIYON 9.9(2023).