Lifestyle improvement and the reduced risk of cardiovascular disease: the China-PAR project

Jiang, Ying-Ying1,2,3; Liu, Fang-Chao2,3; Shen, Chong1,4; Li, Jian-Xin2,3; Huang, Ke-Yong2,3; Yang, Xue-Li5,6; Chen, Ji-Chun2,3; Liu, Xiao-Qing7; Cao, Jie2,3; Chen, Shu-Feng2,3; Yu, Ling8; Zhao, Ying-Xin9; Wu, Xian-Ping10; Zhao, Lian-Cheng2,3; Li, Ying2,3; Hu, Dong-Sheng11,12; Huang, Jian-Feng2,3; Lu, Xiang-Feng2,3; Gu, Dong-Feng1,2,3,13

2023

10.26599/1671-5411.2023.11.005

JOURNAL OF GERIATRIC CARDIOLOGY   影响因子和分区

1671-5411

["BACKGROUND The benefits of healthy lifestyles are well recognized. However, the extent to which improving unhealthy lifestyles reduces cardiovascular disease (CVD) risk needs to be discussed. We evaluated the impact of lifestyle improvement on CVD incidence using data from the China-PAR project (Prediction for Atherosclerotic Cardiovascular Disease Risk in China).","METHODS A total of 12,588 participants free of CVD were followed up for three visits after the baseline examination. Changes in four lifestyle factors (LFs) (smoking, diet, physical activity, and alcohol consumption) were assessed through questionnaires from the baseline to the first follow-up visit. Cox proportional hazard models were used to estimate hazard ratios (HRs) and corresponding 95% confidence intervals (CIs). The risk advancement periods (RAPs: the age difference between exposed and unexposed participants reaching the same incident CVD risk) and population-attributable risk percentage (PAR%) were also calculated.","RESULTS A total of 909 incident CVD cases occurred over a median follow-up of 11.14 years. Compared with maintaining 0-1 healthy LFs, maintaining 3-4 healthy LFs was associated with a 40% risk reduction of incident CVD (HR = 0.60, 95% CI: 0.45-0.79) and delayed CVD risk by 6.31 years (RAP: -6.31 [-9.92, -2.70] years). The PAR% of maintaining 3-4 unhealthy LFs was 22.0% compared to maintaining 0-1 unhealthy LFs. Besides, compared with maintaining two healthy LFs, improving healthy LFs from 2 to 3-4 was associated with a 23% lower risk of CVD (HR = 0.77, 95% CI: 0.60-0.98).","CONCLUSIONS Long-term sustenance of healthy lifestyles or improving unhealthy lifestyles can reduce and delay CVD risk."]

SCI

英语

通讯

Chinese Academy of Medical Sciences Innovation Fund for Medical Sciences["2021-I2M-1-010","2017-I2M-1-004","2019-I2M-2-003"] ; National Natural Science Foundation of China["82030102","12126602"] ; Research Unit of Prospective Cohort of Cardiovascular Diseases and Cancers, Chinese Academy of Medical Sciences[2019RU038]

Cardiovascular System & Cardiology ; Geriatrics & Gerontology

Cardiac & Cardiovascular Systems ; Geriatrics & Gerontology

WOS:001115081200002

TSINGHUA UNIV PRESS

Web of Science

1.Nanjing Med Univ, Sch Publ Hlth, Dept Epidemiol, Ctr Global Hlth, Nanjing, Peoples R China
2.Chinese Acad Med Sci & Peking Union Med Coll, Fuwai Hosp, Dept Epidemiol, Natl Ctr Cardiovasc Dis, Beijing, Peoples R China
3.Chinese Acad Med Sci, Key Lab Cardiovasc Epidemiol, Beijing, Peoples R China
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5.Tianjin Med Univ, Tianjin Key Lab Environm Nutr & Publ Hlth, Sch Publ Hlth, Tianjin, Peoples R China
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7.Guangdong Prov Peoples Hosp & Cardiovasc Inst, Div Epidemiol, Guangzhou, Peoples R China
8.Fujian Prov Hosp, Dept Cardiol, Fuzhou, Peoples R China
9.Shandong Acad Med Sci, Inst Basic Med, Cardiocerebrovasc Control & Res Ctr, Jinan, Peoples R China
10.Sichuan Ctr Dis Control & Prevent, Chengdu, Peoples R China
11.Zhengzhou Univ, Coll Publ Hlth, Dept Epidemiol & Hlth Stat, Zhengzhou, Peoples R China
12.Shenzhen Univ, Sch Publ Hlth, Dept Epidemiol & Hlth Stat, Hlth Sci Ctr, Shenzhen, Peoples R China
13.Southern Univ Sci & Technol, Sch Med, Shenzhen, Peoples R China

Jiang, Ying-Ying,Liu, Fang-Chao,Shen, Chong,et al. Lifestyle improvement and the reduced risk of cardiovascular disease: the China-PAR project[J]. JOURNAL OF GERIATRIC CARDIOLOGY,2023,20(11).

Jiang, Ying-Ying.,Liu, Fang-Chao.,Shen, Chong.,Li, Jian-Xin.,Huang, Ke-Yong.,...&Gu, Dong-Feng.(2023).Lifestyle improvement and the reduced risk of cardiovascular disease: the China-PAR project.JOURNAL OF GERIATRIC CARDIOLOGY,20(11).

Jiang, Ying-Ying,et al."Lifestyle improvement and the reduced risk of cardiovascular disease: the China-PAR project".JOURNAL OF GERIATRIC CARDIOLOGY 20.11(2023).