Leisure-time physical activity and the incidence of atrial fibrillation in senior adults: a prospective cohort study

Mei, Yunting1; Huang, Li1; Gong, Cong2; Zhao, Wenjing3; Gui, Ming1; Qiu, Quan4; Wang, Zhiwei5; Chen, Yufeng6; Xie, Yuanling7; Cai, Xueqing8; Yuan, Yue-Shuang9; Zheng, Zhen-Feng10; Xue, Yumei2; Deng, Hai2; Liu, Xudong1

2024-07-10

10.1093/ageing/afae142

AGE AND AGEING   影响因子和分区

0002-0729

1468-2834

Objective Whether physical activity could reduce the risk of atrial fibrillation (AF) remains unclear. This study was to investigate the relationship of leisure-time physical activity (LTPA) with AF incidence among Chinese older adults.Methods A total of 3253 participants aged >= 60 years from the Guangzhou Heart Study were successfully followed between March 2018 and September 2019. LTPA was assessed using a modified Global Physical Activity Questionnaire. AF was ascertained by 12-lead electrocardiograms, 24-hour single-lead Holter and clinical examination. The Cox proportional hazards model was used to the estimate hazard ratio (HR) and 95% confidence interval (CI) after adjustment for confounders, and the population-attributable fraction (PAF) was estimated.Results A total of 76 (2.34%) new-onset cases of AF were identified during a median of 31.13 months of follow-up. After adjustment for confounders, subjects who had LTPA at least 10.0 metabolic equivalent (MET)-hours/week had a 55% lower risk of developing AF (HR: 0.45, 95%CI: 0.25-0.81), and at least 20 MET-hours/week reduced the risk by 45% (HR: 0.55, 95%CI: 0.34-0.92). At least 11% (PAF: 11%, 95%CI: 0%-20%) or 14% (PAF: 14%, 95%CI: 0%-26%) of AF cases could be avoided, respectively, if the subjects do LTPA at least 10 MET-hours/week or 20 MET-hours/week. A significant exposure-response trend was also observed between LTPA and AF risk (Plinear-trend = 0.002). For a specific LTPA, doing housework was associated with a 43% reduced risk, while engaging in ball games was associated with an increased risk.Conclusion This prospective cohort study indicated that a higher LTPA volume was associated with a lower AF risk in Chinese older adults.

leisure-time physical activity atrial fibrillation cohort study older people

SCI

英语

其他

Guangdong Basic and Applied Basic Research Foundation["2022A1515010686","2022A1515110747","2024A1515010973"] ; Medical Science and Technology Research Foundation of Guangdong Province[A2023408] ; Science and Technology Program of Guangzhou City[202102080404]

Geriatrics & Gerontology

Geriatrics & Gerontology

WOS:001267491600001

OXFORD UNIV PRESS

CLINICAL MEDICINE

Web of Science

1.Guangdong Pharmaceut Univ, Sch Publ Hlth, 83 Jianghai Ave, Guangzhou 510310, Peoples R China
2.Southern Med Univ, Guangdong Prov Peoples Hosp, Guangdong Acad Med Sci, Dept Cardiol,Guangdong Cardiovasc Inst, Guangzhou 510080, Peoples R China
3.Southern Univ Sci & Technol, Sch Publ Hlth & Emergency Management, Shenzhen 518055, Peoples R China
4.Guangdong Prov Ctr Dis Control & Prevent, Dept Adm Affairs, Guangzhou 511430, Peoples R China
5.Guangzhou Ctr Dis Control & Prevent, Dept Hlth Hotline 12320, Guangzhou 510440, Peoples R China
6.Guangzhou Yuexiu Dist Ctr Dis Control & Prevent, Dept Community Hlth, Guangzhou 510080, Peoples R China
7.Guangzhou Baiyun St Community Hlth Serv Ctr, Dept Community Hlth, Guangzhou 510080, Peoples R China
8.Guangzhou Dadong St Community Hlth Serv Ctr, Dept Community Hlth, Guangzhou 510080, Peoples R China
9.Guangzhou Xinzao Town Community Hlth Serv Ctr, Dept Community Hlth, Guangzhou 511442, Peoples R China
10.Guangzhou Nancun Town Community Hlth Serv Ctr, Dept Community Hlth, Guangzhou 511442, Peoples R China

Mei, Yunting,Huang, Li,Gong, Cong,et al. Leisure-time physical activity and the incidence of atrial fibrillation in senior adults: a prospective cohort study[J]. AGE AND AGEING,2024,53(7).

Mei, Yunting.,Huang, Li.,Gong, Cong.,Zhao, Wenjing.,Gui, Ming.,...&Liu, Xudong.(2024).Leisure-time physical activity and the incidence of atrial fibrillation in senior adults: a prospective cohort study.AGE AND AGEING,53(7).

Mei, Yunting,et al."Leisure-time physical activity and the incidence of atrial fibrillation in senior adults: a prospective cohort study".AGE AND AGEING 53.7(2024).