题名 | In situ manufacture of hydrogel lubrication coating on damaged tissue to resist adhesion |
作者 | |
通讯作者 | Fan, Zengjie; Ma, Shuanhong; Zhou, Feng |
发表日期 | 2024-07-17
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DOI | |
发表期刊 | |
EISSN | 2666-3864
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卷号 | 5期号:7 |
摘要 | The human body involves many soft interfaces with excellent hydration and lubrication properties to resist biological adhesion. The abdominal cavity, one of the most important parts of soft tissues, commonly generates severe wear and adhesion-related complication upon encountering lubrication failure between the internal organs of the abdominal cavity and the abdominal wall. Here, we report a method for the manufacture of UV-cured hydrogel lubrication coating on damaged cecum tissue. The hydrogel coating consists of methacrylated carboxymethyl chitosan (MA-CMC) and o- nitrobenzene-grafted hyaluronic acid (HA-NB). The coating not only exhibits fast curing time, good bonding strength, as well as matching mechanics with organs but also shows good lubricity and anti-fouling properties. The anti-adhesion performance of the coating is verified in a constructed rat cecum-abdominal wall postoperative adhesion model. The current concept of hydrogel lubrication coating may help accelerate the development and clinical application of soft anti-adhesion materials. |
相关链接 | [来源记录] |
收录类别 | |
语种 | 英语
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学校署名 | 其他
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资助项目 | Strategic Priority Research Program of the Chinese Academy of Sciences[XDB 0470201]
; National Natural Science Foundation of China["22032006","52075522","52322506"]
; Outstanding Youth Fund of Gansu Province[21JR7RA095]
; West Light Foundation, Chinese Academy of Sciences[xbzg-zdsys-202211]
; Key Research Project of Shandong Provincial Natural Science Foundation[ZR2021ZD27]
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WOS研究方向 | Chemistry
; Energy & Fuels
; Materials Science
; Physics
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WOS类目 | Chemistry, Multidisciplinary
; Energy & Fuels
; Materials Science, Multidisciplinary
; Physics, Multidisciplinary
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WOS记录号 | WOS:001274011800001
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出版者 | |
来源库 | Web of Science
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引用统计 | |
成果类型 | 期刊论文 |
条目标识符 | http://sustech.caswiz.com/handle/2SGJ60CL/790031 |
专题 | 工学院_机械与能源工程系 |
作者单位 | 1.Chinese Acad Sci, Lanzhou Inst Chem Phys, State Key Lab Solid Lubricat, Lanzhou 730000, Gansu, Peoples R China 2.Univ Chinese Acad Sci, Coll Mat Sci & Optoelect Technol, Beijing 100049, Peoples R China 3.Lanzhou Univ, Sch Stomatol, Key Lab Dent Maxillofacial Reconstruct & Biol Inte, Lanzhou 730000, Gansu, Peoples R China 4.Southern Univ Sci & Technol, Dept Mech & Energy Engn, Shenzhen 518055, Guangdong, Peoples R China 5.Yantai Zhongke Res Inst Adv Mat & Green Chem Engn, Shandong Lab Adv Mat & Green Manufacture Yantai, Yantai 264006, Shandong, Peoples R China |
推荐引用方式 GB/T 7714 |
Li, Renjie,Hu, Cewen,Gao, Luyao,et al. In situ manufacture of hydrogel lubrication coating on damaged tissue to resist adhesion[J]. CELL REPORTS PHYSICAL SCIENCE,2024,5(7).
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APA |
Li, Renjie.,Hu, Cewen.,Gao, Luyao.,Zhang, Yunlei.,Zhang, Pei.,...&Zhou, Feng.(2024).In situ manufacture of hydrogel lubrication coating on damaged tissue to resist adhesion.CELL REPORTS PHYSICAL SCIENCE,5(7).
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MLA |
Li, Renjie,et al."In situ manufacture of hydrogel lubrication coating on damaged tissue to resist adhesion".CELL REPORTS PHYSICAL SCIENCE 5.7(2024).
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