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题名

A Lego-Like Reconfigurable Microfluidic Stabilizer System with Tunable Fluidic RC Constants and Stabilization Ratios

作者
通讯作者Cheng, Xing
发表日期
2024-07
DOI
发表期刊
EISSN
2072-666X
卷号15
摘要
In microfluidic systems, it is important to maintain flow stability to execute various functions, such as chemical reactions, cell transportation, and liquid injection. However, traditional flow sources, often bulky and prone to unpredictable fluctuations, limit the portability and broader application of these systems. Existing fluidic stabilizers, typically designed for specific flow sources, lack reconfigurability and adaptability in terms of the stabilization ratios. To address these limitations, a modular and standardized stabilizer system with tunable stabilization ratios is required. In this work, we present a Lego-like modular microfluidic stabilizer system, which is fabricated using 3D printing and offers multi-level stabilization combinations and customizable stabilization ratios through the control of fluidic RC constants, making it adaptable to various microfluidic systems. A simplified three-element circuit model is used to characterize the system by straightforwardly extracting the RC constant without intricate calculations of the fluidic resistance and capacitance. By utilizing a simplified three-element model, the stabilizer yields two well-fitted operational curves, demonstrating an R-square of 0.95, and provides an optimal stabilization ratio below 1%. To evaluate the system’s effectiveness, unstable input flow at different working frequencies is stabilized, and droplet generation experiments are conducted and discussed. The results show that the microfluidic stabilizer system significantly reduces flow fluctuations and enhances droplet uniformity. This system provides a new avenue for microfluidic stabilization with a tunable stabilization ratio, and its plug-and-play design can be effectively applied across diverse applications to finely tune fluid flow behaviors in microfluidic devices.
© 2024 by the authors.
收录类别
EI ; SCI
语种
英语
学校署名
第一 ; 通讯
资助项目
The work was financially supported by Shenzhen Science and Technology Innovation Committee for Talent Development (RCJC20200714114436046), the National Natural Science Foundation of China (31927802), and the Guangdong-Hong Kong-Macau Joint Laboratory on Micro-Nano Manufacturing Technology (2021LSYS004).
出版者
EI入藏号
20243116775425
EI主题词
3D printing ; Chemical stability ; Drops ; Energy transfer ; Flow of fluids ; Fluidic devices ; Stabilization ; Timing circuits
EI分类号
Fluid Flow, General:631.1 ; Hydraulic Equipment and Machinery:632.2 ; Microfluidics:632.5.1 ; Pulse Circuits:713.4 ; Control Equipment:732.1 ; Printing Equipment:745.1.1 ; Chemistry:801
来源库
EV Compendex
引用统计
成果类型期刊论文
条目标识符http://sustech.caswiz.com/handle/2SGJ60CL/794458
专题工学院_材料科学与工程系
南方科技大学
作者单位
1.Guangdong-Hong Kong-Macau Joint Laboratory on Micro-Nano Manufacturing Technology, Department of Materials Science and Engineering, Southern University of Science and Technology, No. 1088 Xueyuan Blvd., Shenzhen; 518055, China
2.Department of Mechanical Engineering, University of Birmingham, Edgbaston, Birmingham; B15 2TT, United Kingdom
3.Department of Materials Science and Engineering, National University of Singapore, 9 Engineering Drive 1, Singapore; 117576, Singapore
4.Yangtze Delta Region Institute of Tsinghua University, 705 Yatai Road, Jiaxing; 314006, China
第一作者单位材料科学与工程系
通讯作者单位材料科学与工程系
第一作者的第一单位材料科学与工程系
推荐引用方式
GB/T 7714
Zhuge, Wuyang,Li, Weihao,Wang, Kaimin,et al. A Lego-Like Reconfigurable Microfluidic Stabilizer System with Tunable Fluidic RC Constants and Stabilization Ratios[J]. Micromachines,2024,15.
APA
Zhuge, Wuyang.,Li, Weihao.,Wang, Kaimin.,Chen, Zhuodan.,Wu, Chunhui.,...&Cheng, Xing.(2024).A Lego-Like Reconfigurable Microfluidic Stabilizer System with Tunable Fluidic RC Constants and Stabilization Ratios.Micromachines,15.
MLA
Zhuge, Wuyang,et al."A Lego-Like Reconfigurable Microfluidic Stabilizer System with Tunable Fluidic RC Constants and Stabilization Ratios".Micromachines 15(2024).
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