Multi-omics in nanoplastic research: a spotlight on aquatic life

Helal, Mohamed1,2; Liu, Min3; Chen, Honghong4,5,6; Fang, Mingliang3,7; Qiu, Wenhui4; Kjeldsen, Frank8; Tollefsen, Knut Erik9,10; Thiyagarajan, Vengatesen11; Holbech, Henrik1; Xu, Elvis Genbo1

2024-11-01

10.1007/s11783-024-1893-3

FRONTIERS OF ENVIRONMENTAL SCIENCE & ENGINEERING   影响因子和分区

2095-2201

2095-221X

Amidst increasing concerns about plastic pollution's impacts on ecology and health, nanoplastics are gaining global recognition as emerging environmental hazards. This review aimed to examine the complex molecular consequences and underlying fundamental toxicity mechanisms reported from the exposure of diverse aquatic organisms to nanoplastics. Through the comprehensive examination of transcriptomics, proteomics, and metabolomics studies, we explored the intricate toxicodynamics of nanoplastics in aquatic species. The review raised essential questions about the consistency of findings across different omics approaches, the value of combining these omics tools to understand better and predict ecotoxicity, and the potential differences in molecular responses between species. By amalgamating insights from 37 omics studies (transcriptome 22, proteome six, and metabolome nine) published from 2013 to 2023, the review uncovered both shared and distinct toxic effects and mechanisms in which nanoplastics can affect aquatic life, and recommendations were provided for advancing omics-based research on nanoplastic pollution. This comprehensive review illuminates the nuanced connections between nanoplastic exposure and aquatic ecosystems, offering crucial insights into the complex mechanisms that may drive toxicity in aquatic environments.

Ecotoxicity Transcriptomics Metabolomics Proteomics Plastic pollution Toxicity mechanisms

SCI ; EI

英语

其他

Sapere Aude Research Leader program from the Danish Council for Independent Research[0165-00056B] ; Research Council of Norway[315969] ; NIVA's Computational Toxicology Program (NCTP)[342628]

Engineering ; Environmental Sciences & Ecology

Engineering, Environmental ; Environmental Sciences

WOS:001293670300001

HIGHER EDUCATION PRESS

Web of Science

1.Univ Southern Denmark, Dept Biol, DK-5230 Odense, Denmark
2.Natl Inst Oceanog & Fisheries NIOF, Cairo 11865, Egypt
3.Nanyang Technol Univ, Sch Civil & Environm Engn, Singapore 639798, Singapore
4.Southern Univ Sci & Technol, Sch Environm Sci & Engn, Guangdong Prov Key Lab Soil & Groundwater Pollut C, Shenzhen 518055, Peoples R China
5.Eastern Inst Technol, Eastern Inst Adv Study, Ningbo 315200, Peoples R China
6.Shanghai Jiao Tong Univ, Sch Environm Sci & Engn, Shanghai 200240, Peoples R China
7.Fudan Univ, Dept Environm Sci & Engn, Shanghai 200433, Peoples R China
8.Univ Southern Denmark, Dept Biochem & Mol Biol, DK-5230 Odense, Denmark
9.Norwegian Inst Water Res NIVA, N-0579 Oslo, Norway
10.Norwegian Univ Life Sci NMBU, N-1432 As, Norway
11.Univ Hong Kong, Swire Inst Marine Sci, Sch Biol Sci, Hong Kong 999077, Peoples R China

Helal, Mohamed,Liu, Min,Chen, Honghong,et al. Multi-omics in nanoplastic research: a spotlight on aquatic life[J]. FRONTIERS OF ENVIRONMENTAL SCIENCE & ENGINEERING,2024,18(11).

Helal, Mohamed.,Liu, Min.,Chen, Honghong.,Fang, Mingliang.,Qiu, Wenhui.,...&Xu, Elvis Genbo.(2024).Multi-omics in nanoplastic research: a spotlight on aquatic life.FRONTIERS OF ENVIRONMENTAL SCIENCE & ENGINEERING,18(11).

Helal, Mohamed,et al."Multi-omics in nanoplastic research: a spotlight on aquatic life".FRONTIERS OF ENVIRONMENTAL SCIENCE & ENGINEERING 18.11(2024).