Centrifugated lateral flow assay strips based on dual-emission carbon dots modified with europium ions for ratiometric determination and on-site discrimination of tetracyclines in environment

Hu，Houwen1; Xing，Haoming1; Zhang，Yihao1; Liu，Xinru1; Gao，Sineng1; Wang，Linfan1; Li，Tingting1,2; Zhang，Ting3; Chen，Da1

2024-11-15

10.1016/j.scitotenv.2024.175478

Science of the Total Environment   影响因子和分区

0048-9697

1879-1026

Due to the serious detrimental impact on human health, antibiotic pollution particularly tetracyclines residues has become a serious problem. Herein, a multiple response fluorescent probe consisted of dual-emission carbon dots and Eu (D-CDs@Eu) is designed for the determination and discrimination of tetracyclines (TCs). Specifically, the carboxyl and amidogen group of dual-emission carbon dots (D-CDs) can coordinate with Eu to form the D-CDs@Eu. Upon adding TCs, the fluorescence intensities of D-CDs at 405 nm and 495 nm are quenched due to inner filter effect (IFE) and the localization of fluorescence resonance energy transfer (L-FRET) between the D-CDs@Eu and TC. Simultaneously, the D-CDs@Eu may chelate with TCs to enhance the occurrence of antenna effect, while the characteristic peaks of Eu at 590 nm and 615 nm are enhanced. On these bases, the TCs detection is achieved with low detection limits from 46.7 to 72.0 nM. Additionally, through the distinct efficiencies of L-FRET, the discrimination of TCs is achieved. Moreover, a novel centrifugated lateral flow assay strips (CLFASs) device is developed by integrating the D-CDs@Eu, lateral flow assay strips and smartphone using RGB variations for TCs detection, achieving remarkable recoveries (98.6–103.7 %) in real samples. Therefore, this CLFASs device provides a reliable approach for the TCs detection, demonstrating potential applications.

Centrifugated lateral flow assay strips Determination and discrimination Dual-emission carbon dots Europium ions Tetracyclines

英语

其他

ENVIRONMENT/ECOLOGY

2-s2.0-85201198312

Scopus

1.Department of Microelectronic Science and Engineering,School of Physical Science and Technology,Ningbo University,Ningbo,315211,China
2.Department of Materials Science and Engineering,Shenzhen Key Laboratory of Full Spectral Solar Electricity Generation (FSSEG),Southern University of Science and Technology,Shenzhen,518055,China
3.Department of Chemical Engineering,Ningbo Polytechnic,Ningbo,315800,China

Hu，Houwen,Xing，Haoming,Zhang，Yihao,et al. Centrifugated lateral flow assay strips based on dual-emission carbon dots modified with europium ions for ratiometric determination and on-site discrimination of tetracyclines in environment[J]. Science of the Total Environment,2024,951.

Hu，Houwen.,Xing，Haoming.,Zhang，Yihao.,Liu，Xinru.,Gao，Sineng.,...&Chen，Da.(2024).Centrifugated lateral flow assay strips based on dual-emission carbon dots modified with europium ions for ratiometric determination and on-site discrimination of tetracyclines in environment.Science of the Total Environment,951.

Hu，Houwen,et al."Centrifugated lateral flow assay strips based on dual-emission carbon dots modified with europium ions for ratiometric determination and on-site discrimination of tetracyclines in environment".Science of the Total Environment 951(2024).