Leaf Senescence Database v5.0: A Comprehensive Repository for Facilitating Plant Senescence Research

Zhao, Yaning1; Zhang, Yang2,3,4,5; Li, Shichun1; Tan, Shuya1; Cao, Jie1; Wang, Hou-Ling1; Luo, Jingchu6,7; Guo, Hongwei8; Zhang, Zhang2,3,4,5; Li, Zhonghai1

2024-09-01

10.1016/j.jmb.2024.168530

JOURNAL OF MOLECULAR BIOLOGY   影响因子和分区

0022-2836

1089-8638

Through an extensive literature survey, we have upgraded the Leaf Senescence Database (LSD v5.0; https://ngdc.cncb.ac.cn/lsd/), a curated repository of comprehensive senescence-associated genes (SAGs) and their corresponding mutants. Since its inception in 2010, LSD undergoes frequent updates to encompass the latest advances in leaf senescence research and its current version comprises a high-quality collection of 31,740 SAGs and 1,209 mutants from 148 species, which were manually searched based on robust experimental evidence and further categorized according to their functions in leaf senescence. Furthermore, LSD was greatly enriched with comprehensive annotations for the SAGs through meticulous curation using both manual and computational methods. In addition, it was equipped with user-friendly web interfaces that facilitate text queries, BLAST searches, and convenient download of SAG sequences for localized analysis. Users can effortlessly navigate the database to access a plethora of information, including literature references, mutants, phenotypes, multi-omics data, miRNA interactions, homologs in other plants, and cross-links to various databases. Taken together, the upgraded version of LSD stands as the most comprehensive and informative plant senescence-related database to date, incorporating the largest collection of SAGs and thus bearing great utility for a wide range of studies related to plant senescence. (c) 2024 Elsevier Ltd. All rights reserved.

leaf senescence senescence-associated genes database multi-omics LSD

SCI

英语

其他

National Natural Science Foundation of China["32170345","31970196","32030021"] ; Beijing Municipal Natural Science Foundation[5232015] ; National Key Research and Development Program of China[2019YFA0903904] ; Open Research Fund of the National Center for Protein Sciences at Peking University in Beijing[KF-202304]

Biochemistry & Molecular Biology

Biochemistry & Molecular Biology

WOS:001307763200001

ACADEMIC PRESS LTD- ELSEVIER SCIENCE LTD

Web of Science

1.Beijing Forestry Univ, Coll Biol Sci & Technol, State Key Lab Tree Genet & Breeding, Beijing 100083, Peoples R China
2.Chinese Acad Sci, Beijing Inst Genom, Natl Genom Data Ctr, Beijing 100101, Peoples R China
3.Chinese Acad Sci, Beijing Inst Genom, CAS Key Lab Genome Sci & Informat, Beijing 100101, Peoples R China
4.China Natl Ctr Bioinformat, Beijing 100101, Peoples R China
5.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
6.Peking Univ, Coll Life Sci, Beijing 100871, Peoples R China
7.Peking Univ, Ctr Bioinformat, Beijing 100871, Peoples R China
8.Southern Univ Sci & Technol SUSTech, Inst Plant & Food Sci, Dept Biol, Shenzhen 518055, Guangdong, Peoples R China

Zhao, Yaning,Zhang, Yang,Li, Shichun,et al. Leaf Senescence Database v5.0: A Comprehensive Repository for Facilitating Plant Senescence Research[J]. JOURNAL OF MOLECULAR BIOLOGY,2024,436(17).

Zhao, Yaning.,Zhang, Yang.,Li, Shichun.,Tan, Shuya.,Cao, Jie.,...&Li, Zhonghai.(2024).Leaf Senescence Database v5.0: A Comprehensive Repository for Facilitating Plant Senescence Research.JOURNAL OF MOLECULAR BIOLOGY,436(17).

Zhao, Yaning,et al."Leaf Senescence Database v5.0: A Comprehensive Repository for Facilitating Plant Senescence Research".JOURNAL OF MOLECULAR BIOLOGY 436.17(2024).