| 题名 | Kinetic-thermodynamic correlation of conformational changes in ammonium complexes of a flexible naphthocage |
| 作者 | |
| 通讯作者 | Au-Yeung, Ho Yu |
| 发表日期 | 2024-08-01
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| DOI | |
| 发表期刊 | |
| ISSN | 2041-6520
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| EISSN | 2041-6539
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| 摘要 | ["Conformational changes in non-covalent complexes are of fundamental importance to many chemical and biological processes. Yet, these low-energy structural changes are usually fast and difficult to monitor, which poses challenges in their detailed kinetic understanding. The correlation between kinetics and thermodynamics of the conformational change of a model supramolecular system featuring a flexible naphthocage and quaternary ammonium guests is described in this work. Guest binding initially locks the host in two major conformations, which then equilibrates over time to the more stable conformer. The overall rate of the system to attain conformational equilibrium is found to inversely correlate with the thermodynamic stability of the host-guest complexes, and hence not only can the kinetic parameters of the conformational exchange be predicted from the easily obtainable thermodynamic data, but the kinetic profile can also be rationalized by using the structural properties of the different guests.","Correlation between the guest structure, binding thermodynamics and conformational exchange kinetics is established for a series of ammonium complexes of a flexible cage."] |
| 相关链接 | [来源记录] |
| 收录类别 | |
| 语种 | 英语
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| 学校署名 | 其他
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| 资助项目 | Research Grants Council, University Grants Committee["22125105","22101125"]
; National Natural Science Foundation of China[JCYJ20180504165810828]
; CAS-Croucher Funding Scheme for Joint Laboratories[C7075-21G]
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| WOS研究方向 | Chemistry
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| WOS类目 | Chemistry, Multidisciplinary
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| WOS记录号 | WOS:001309522600001
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| 出版者 | |
| 来源库 | Web of Science
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| 引用统计 | |
| 成果类型 | 期刊论文 |
| 条目标识符 | http://sustech.caswiz.com/handle/2SGJ60CL/828896 |
| 专题 | 理学院_化学系 深圳格拉布斯研究院 |
| 作者单位 | 1.Univ Hong Kong, Dept Chem, Hong Kong, Peoples R China 2.Univ Hong Kong, State Key Lab Synthet Chem, Hong Kong, Peoples R China 3.Southern Univ Sci & Technol, Dept Chem, Shenzhen 518055, Peoples R China 4.Southern Univ Sci & Technol, Shenzhen Grubbs Inst, Guangdong Prov Key Lab Catalysis, Shenzhen 518055, Peoples R China 5.Shenzhen Univ, Coll Mat Sci & Engn, Shenzhen Key Lab New Informat Display & Storage Ma, Shenzhen 518055, Peoples R China |
| 第一作者单位 | 化学系; 深圳格拉布斯研究院 |
| 推荐引用方式 GB/T 7714 |
He, Shan,Quan, Mao,Yang, Liu-Pan,et al. Kinetic-thermodynamic correlation of conformational changes in ammonium complexes of a flexible naphthocage[J]. CHEMICAL SCIENCE,2024.
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| APA |
He, Shan,Quan, Mao,Yang, Liu-Pan,Au-Yeung, Ho Yu,&Jiang, Wei.(2024).Kinetic-thermodynamic correlation of conformational changes in ammonium complexes of a flexible naphthocage.CHEMICAL SCIENCE.
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| MLA |
He, Shan,et al."Kinetic-thermodynamic correlation of conformational changes in ammonium complexes of a flexible naphthocage".CHEMICAL SCIENCE (2024).
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| 条目包含的文件 | 条目无相关文件。 | |||||
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