南方科技大学知识苑(SUSTech KC): Ï -Bridge Regulates Donor-Acceptor Interactions for Long-Wavelength Photoacoustic Imaging and Enhanced Photothermal Therapy

题名	Ï -Bridge Regulates Donor-Acceptor Interactions for Long-Wavelength Photoacoustic Imaging and Enhanced Photothermal Therapy
作者	Gu, Ying 1,2,3 ; Lai, Hanjian 2,3 ; Ruan, Shijie 4 ; Zhu, Yulin1,2,3 ; Ding, Pengbo 5,6 ; Fan, Guiling 1; Xi, Lei4 ; Guo, Liang7 ; He, Feng2,3 ; Tian, Leilei1
通讯作者	He, Feng; Tian, Leilei
发表日期	2024-08-01
DOI	10.1021/acsmaterialslett.4c01315
发表期刊	ACS MATERIALS LETTERS 影响因子和分区
EISSN	2639-4979
摘要	Acceptor-donor-acceptor (A-D-A) structured pi-conjugated molecules emerge as a new class of phototheranostic materials. The pi-bridge has rarely been investigated for structure engineering compared with the D and A units. This work reveals that changing ethylene into a butadiene pi-bridge can efficiently extend absorption wavelength and promote the nonradiative transition. Specifically, the butadiene pi-bridge not only extends the pi-conjugation length but also disrupts the SO interlocking, which facilitates intramolecular torsions and rotations and enhances the intramolecular charge transfer for the molecule with butadiene pi-bridge. As a result, very broad absorption with a 70 nm red-shift is observed, and the power conversion efficiency (PCE) of BTVIC nanoparticles reaches 82.6%. Ultimately, photoacoustic imaging (PAI)-guided photothermal therapy (PTT) applications in vivo demonstrate a deep penetration depth of over 7 mm and an efficient anti-tumor effect. This work illustrates that modifying the pi-bridge is a practical strategy for regulating A-D-A interactions and developing more efficient phototheranostic agents.
相关链接	[来源记录]
收录类别	SCI
语种	英语
学校署名	第一 ; 通讯
资助项目	Guangdong Basic and Applied Basic Research Foundation["2024A1515012055","2024B1515020077"] ; National Natural Science Foundation of China["22225504","52176075"] ; Guangdong Provincial Key Laboratory of Catalysis[2020B121201002] ; Shenzhen Fundamental Research Programs[JCYJ20220530113612027] ; Shenzhen Sci-Tech Fund[KQTD20170810111314625]
WOS研究方向	Materials Science
WOS类目	Materials Science, Multidisciplinary
WOS记录号	WOS:001308503400001
出版者	AMER CHEMICAL SOC
来源库	Web of Science
引用统计
成果类型	期刊论文
条目标识符	http://sustech.caswiz.com/handle/2SGJ60CL/828915
专题	工学院_材料科学与工程系南方科技大学工学院_机械与能源工程系理学院_化学系深圳格拉布斯研究院工学院_生物医学工程系
作者单位	1.Southern Univ Sci & Technol, Dept Mat Sci & Engn, Shenzhen 518055, Guangdong, Peoples R China 2.Southern Univ Sci & Technol, Shenzhen Grubbs Inst, Dept Chem, Shenzhen 518055, Guangdong, Peoples R China 3.Southern Univ Sci & Technol, Guangdong Prov Key Lab Catalysis, Shenzhen 518055, Guangdong, Peoples R China 4.Southern Univ Sci & Technol, Dept Biomed Engn, Shenzhen 518055, Guangdong, Peoples R China 5.Southern Univ Sci & Technol, Dept Mech & Energy Engn, Shenzhen 518055, Guangdong, Peoples R China 6.Hong Kong Univ Sci & Technol, Dept Chem, Hong Kong 999077, Peoples R China 7.Southern Univ Sci & Technol, SUSTech Energy Inst Carbon Neutral, Dept Mech & Energy Engn, Shenzhen 518055, Guangdong, Peoples R China
第一作者单位	材料科学与工程系; 化学系; 深圳格拉布斯研究院; 南方科技大学
通讯作者单位	化学系; 深圳格拉布斯研究院; 南方科技大学; 材料科学与工程系
第一作者的第一单位	材料科学与工程系
推荐引用方式 GB/T 7714	Gu, Ying,Lai, Hanjian,Ruan, Shijie,et al. Ï -Bridge Regulates Donor-Acceptor Interactions for Long-Wavelength Photoacoustic Imaging and Enhanced Photothermal Therapy[J]. ACS MATERIALS LETTERS,2024.
APA	Gu, Ying.,Lai, Hanjian.,Ruan, Shijie.,Zhu, Yulin.,Ding, Pengbo.,...&Tian, Leilei.(2024).Ï -Bridge Regulates Donor-Acceptor Interactions for Long-Wavelength Photoacoustic Imaging and Enhanced Photothermal Therapy.ACS MATERIALS LETTERS.
MLA	Gu, Ying,et al."Ï -Bridge Regulates Donor-Acceptor Interactions for Long-Wavelength Photoacoustic Imaging and Enhanced Photothermal Therapy".ACS MATERIALS LETTERS (2024).